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Model of GATA-3 expression. (A) Basic molecular processes involved in the regulation of GATA-3. Solid and dashed arrows indicate reaction steps and regulatory interactions, respectively. Several modification steps (e.g., acetylation, phosphorylation) have been implicated by experimental studies, but their involvement in regulation of GATA-3's transcriptional activity remains to be fully defined. (B) Scheme of the mathematical model.
