Table 6. In vitro drug release profiles of F1 to F9 batches .
|
Time (Hours) |
% CDR |
||||||||
|
- |
F1 |
F2 |
F3 |
F4 |
F5 |
F6 |
F7 |
F8 |
F9 |
|
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
1 |
5.50 |
6.80 |
7.60 |
6.20 |
7.56 |
4.53 |
8.19 |
5.20 |
2.06 |
|
2 |
14.33 |
15.56 |
14.55 |
14.85 |
15.6 |
12.16 |
13.03 |
13.90 |
14.88 |
|
3 |
22.66 |
20.15 |
19.56 |
23.45 |
22.63 |
21.60 |
24.83 |
21.70 |
24.15 |
|
4 |
29.63 |
27.00 |
25.45 |
30.12 |
30.89 |
30.90 |
33.5 |
28.00 |
31.02 |
|
5 |
38.23 |
35.78 |
32.74 |
38.40 |
36.45 |
39.35 |
42.16 |
36.57 |
38.41 |
|
6 |
46.06 |
44.56 |
41.58 |
45.61 |
48.56 |
47.88 |
51.03 |
45.00 |
47.28 |
|
7 |
54.00 |
51.74 |
49.12 |
52.19 |
57.65 |
54.26 |
60.23 |
51.79 |
53.21 |
|
8 |
63.23 |
60.12 |
58.07 |
59.46 |
64.23 |
62.45 |
66.85 |
57.60 |
57.18 |
|
9 |
71.28 |
69.24 |
66.05 |
65.58 |
72.24 |
69.12 |
74.52 |
64.12 |
62.00 |
|
10 |
79.55 |
76.00 |
74.24 |
73.12 |
79.57 |
75.00 |
80.05 |
70.00 |
69.35 |
|
11 |
84.72 |
83.99 |
80.70 |
80.40 |
84.26 |
81.76 |
87.69 |
77.91 |
74.59 |
|
12 |
88.69 |
86.56 |
87.21 |
88.58 |
87.69 |
86.26 |
91.58 |
83.26 |
79.60 |
CDR: Cummulative drug release