Table 5. Calibration curve outcomes .
|
Analyte |
Nominal concentration (ng/mL) |
Mean found concentration (ng/mL) |
CV% |
Parameters |
|
DOR |
2.5 |
2.1 |
00% |
• Slope: 0.00875556 • Y-intercept: 0.015462 • r2: 0.99929 • Regression equation: y = 0.00875556x + 0.015462 • Linearity range: 2.5 - 1000 ng/mL |
|
10 |
11.1 |
11% |
||
|
50 |
49.8 |
6.8% |
||
|
100 |
107.3 |
7.3% |
||
|
500 |
476.3 |
-4.74% |
||
|
1000 |
992.2 |
-0.78% |
||
|
TDF |
2.5 |
2.2 |
-12.0% |
• Slope: 0.00321555 • Y-intercept: 0.00158833 • r2: 0.993768 • Regression equation: y = 0.00321555x + 0.00158833 • Linearity range: 2.5 - 1000 ng/mL |
|
10 |
9.2 |
-8.0% |
||
|
50 |
51.1 |
4.2% |
||
|
100 |
111.5 |
11.5% |
||
|
500 |
481.6 |
-3.68% |
||
|
1000 |
1007.1 |
0.71% |
||
|
LAM |
2.5 |
2.6 |
4% |
• Slope: 0.000851902 • Y-intercept: 0.00409457 • r2: 0.998670 • Regression equation: y = 0.000851902x + 0.00409457 • Linearity range: 2.5 - 1000 ng/mL |
|
10 |
8.7 |
-13% |
||
|
50 |
50.4 |
4.4% |
||
|
100 |
109.4 |
9.4% |
||
|
500 |
445.9 |
-10.82% |
||
|
1000 |
1040.9 |
4.09% |
DOR: Doravirine, LAM: Lamivudine, TDF: Tenofovir Disoproxil Fumarate, CV: Coefficient of variation