Table 6. Outcomes of precision .
|
Analyte |
Level of QC |
Nominal concentration (ng/mL) |
Intra batch |
Inter batch |
||
|
Mean found concentration (ng/mL) |
CV% |
Mean found concentration (ng/mL) |
CV% |
|||
|
DOR |
LQC |
7.4 |
6.8 |
-1.08 |
6.5 |
-1.18 |
|
MQC |
480 |
439.9 |
-4.23 |
423.4 |
-5.31 |
|
|
HQC |
900 |
991.3 |
5.06 |
1070.2 |
7.01 |
|
|
LAM |
LQC |
7.4 |
8.5 |
5.23 |
8.8 |
6.54 |
|
MQC |
480 |
501.9 |
8.8 |
521.4 |
5.6 |
|
|
HQC |
900 |
986.7 |
5.23 |
1026.1 |
7.1 |
|
|
TDF |
LQC |
7.4 |
7.9 |
2.1 |
8.5 |
2.6 |
|
MQC |
480 |
501.4 |
4.2 |
522.8 |
6.2 |
|
|
HQC |
900 |
912.1 |
2.2 |
1005.6 |
5.9 |
|
DOR: Doravirine, LAM: Lamivudine, TDF: Tenofovir Disoproxil Fumarate, CV: Coefficient of variation, HQC: High-Quality Control, MQC: Middle-Quality Control, LQC: Low-Quality Control