Table 8. Outcomes of Doravirine Matrix Effect .
|
Analyte |
Doravirine |
||
|
Analyte MF |
ISTD MF |
IS normalized factor |
|
|
Lot-I |
0.791 |
0.720 |
1.099 |
|
Lot-II |
0.747 |
0.606 |
1.233 |
|
Lot-III |
0.637 |
0.620 |
1.027 |
|
Lot-IV |
0.762 |
0.712 |
1.070 |
|
Lot-V |
0.711 |
0.696 |
1.022 |
|
Lot-VI |
0.667 |
0.709 |
0.941 |
|
Mean |
- |
- |
1.065 |
|
SD% |
- |
- |
0.098 |
|
CV% |
- |
- |
9.204 |
MF: Matrix factor, ISTD: Internal standard, CV: Coefficient of variation, SD: Standard deviation