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. Author manuscript; available in PMC: 2025 Aug 1.
Published in final edited form as: Sci Transl Med. 2025 Jun 4;17(801):eadq1810. doi: 10.1126/scitranslmed.adq1810

Figure 1. Overview of the human cerebroventricular system.

Figure 1.

(A) Illustration of the choroid plexus (ChP) epithelium with component cell types. (B) Systemic movement of cerebrospinal fluid (CSF) produced by the ChP epithelium. CSF is thought to traverse the subarachnoid space and to be reabsorbed into the systemic circulation via the arachnoid granulations (B) or the cranial meninges and the glymphatic system (C). Abbreviations: aqueduct of Sylvius (AS), cerebrospinal fluid (CSF), ChP (CP), foramen of Monro (FM), foramen of Luschka (FM), fourth ventricle (4V), lateral ventricle (LV), interstitial fluid (ISF), third ventricle (3V), and subventricular zone (SVZ).