Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2005 Sep 23;1(3):e38. doi: 10.1371/journal.pgen.0010038

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

(A) FISH to interphase pq/+ chromosome spreads with a p3pTVA transgene probe (red) locates the transgene insertion on mouse Chromosome 3 between BACs RP23-338I15 (yellow) and RP23-296I12 (green).

(B) The genomic region defined by BAC FISH localization contained six known or predicted genes, one of which, Serpini2, is highly expressed in pancreas and adipose tissue. PCR primer sets A–P (Table S1) were used to characterize and define the identified ~210-kb deletion, indicated by red dashed line. PCR primer sets that correspond to known and predicted exon sequences are indicated by black vertical dashed lines. The genomic deletion encompassed the entire Serpini2 gene locus and exons 4 to 17 of the predicted gene E-62199.1/E-38943.1.