Table 3.

Comparison of HIIT vs. MICT in subjects with MASLD^74-76

	HIIT	MICT	Remark
Metabolic parameters	Improved	Improved	HIIT was superior to MICT.
Reduction of intrahepatic fat	Yes	Yes	HIIT similar or superior to MICT
Mechanisms of improvement	Reduce anaerobic glycolysis Enhance lactate clearance Increase in muscle cell mitochondria and capillary density in muscle tissue	Similar to HIIT
Features	Shorter time required Rapid improvement of cardiopulmonary fitness Higher post-exercise oxygen consumption Improved adherence in diseased cohorts	Traditional and well established Improve quality of life

HIIT, high-intensity interval training; MICT, moderate-intensity continuous training; MASLD, metabolic dysfunction-associated steatotic liver disease.