Fig. 6.

Animal experiments for the assessment of the treatment of OA with Res@Lipo@HMs. A) Representative images of H&E staining. B) OARSI scores of articular cartilage in each group. C) Representative images of safranin O-fast green staining (S-F staining). D) Relative GAG content in each group. E) Representative sections of terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling (TUNEL) staining for apoptotic cells. F) Quantification of TUNEL-positive cells. G) Representative sections of immunohistochemical staining for collagen II. H) Quantification of collagen II-positive cells. I) Representative sections of immunohistochemical staining for MMP13. J) Quantification of MMP13-positive cells. (n = 6 for each group) (ns: not significant; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)