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. 2025 Jul 24;12(7):ENEURO.0430-24.2025. doi: 10.1523/ENEURO.0430-24.2025

Table 2.

Summary of the key PLS analyses results

Mean-centered PLS Age and sustained attention bPLS Age and selective attention bPLS Age and executive attention bPLS Combined bPLS of SC, FC, and SC–FC coupling with age
Metrics with significant LVs FC weighted degree SC modularity SC modularity SC modularity SC weighted degreeb, FC weighted degree, and SC–FC coupling
FC local clustering SC weighted degreea SC weighted degree SC weighted degree
SC–FC coupling SC local clustering SC local clustering

The brain metrics with significant (p < 0.05) LVs from the mean-centered PLS analyses and bPLS analyses. Analyses with two significant LVs are denoted with a. The combined analysis with SC weighted degree, FC weighted degree, and SC–FC coupling with age as the dependent variable (combined bPLS of SC, FC, and SC–FC coupling with age) identified SC as the dominant predictor of age, as marked by b. bPLS analyses with age and all three attention measures included were also conducted (Extended Data Table 2-1) and compared with the separate analyses (Extended Data Tables 2-2, 2-3). SC, structural connectivity; FC, functional connectivity.