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Particle size distribution results for two APIs
| Drug | D(μm) | Original API | Air-flow pulverization | Ultra-micronization |
|---|---|---|---|---|
| Neomycin sulfate | D10 | 6.530 ± 0.031 | 5.580 ± 0.025 | 5.110 ± 0.021 |
| D50 | 31.29 ± 0.042 | 16.04 ± 0.027 | 11.90 ± 0.028 | |
| D90 | 84.68 ± 0.025 | 42.74 ± 0.045 | 26.38 ± 0.032 | |
| Triamcinolone acetonide | D10 | 5.421 ± 0.024 | 2.192 ± 0.032 | 1.269 ± 0.034 |
| D50 | 6.342 ± 0.015 | 5.455 ± 0.036 | 4.496 ± 0.019 | |
| D90 | 11.379 ± 0.02 | 10.590 ± 0.032 | 7.079 ± 0.026 |
