Fig 2.

Secondary structure model of the B. subtilis glyQS leader RNA. Sequence is shown from the transcription start site (+1) through the end of the leader region terminator; the alternate antiterminator is shown above the terminator. The structure is based on the covariation model of T box family leaders (2, 5). Major conserved features are labeled, and conserved primary sequence elements are denoted with asterisks. The specifier sequence residues are boxed. The glyQS sequence was obtained from the B. subtilis genome sequence (11); DNA sequencing of this region revealed a substitution of A for U at position +6. The residues in brackets (113–122) are replaced by the stem II and IIA/B elements in most T box family leaders, including B. subtilis tyrS.