Table 3. Correlations between functional connectivity and CBCL-externalizing obtained from the standard, motion-ordered, and bagging methods as a function of sample size across the 3 low-motion racial/ethnic groups.
The standard method corresponded to the brain-behavior associations derived from the full fMRI timeseries of the low-motion youth with a mean FD < 0.20 mm. The motion-ordered method corresponded to the brain-behavior associations derived from the scrubbed fMRI timeseries ranked and thresholded by their 100 least motion-corrupted timepoints (0 < FD < 0.20 mm) to construct the functional connectivity matrices of the low-motion youth. The bagging method corresponded to the brain-behavior associations derived from the scrubbed fMRI timeseries ranked and thresholded by their 100 least motion-corrupted timepoints (0 < FD < 0.20 mm) from which 100 timepoints were bootstrapped across 500 iterations to construct the functional connectivity matrices of the low-motion youth. The sample sizes were bootstrapped at 11 logarithmically-spaced N intervals: White N ∈ {25, 39, 62, 97, 152, 238, 374, 586, 920, 1444, 2266}; Black N ∈ {25, 33, 44, 58, 77, 101, 134, 177, 234, 310, 410}; Hispanic N ∈ {25, 35, 48, 67, 93, 129, 179, 249, 345, 480, 666}. For each low-motion racial/ethnic group and behavior, we computed a total of 11 intervals x 500 bootstrap N samples = 5,500 standard and motion-ordered correlations. For each low-motion racial/ethnic group and behavior, we computed a total of 11 intervals x 500 bootstrap N samples x 500 bootstrap timepoints = 2.75 million bagged correlations. For each racial/ethnic group, the brain-behavior Rs and 95% CI are shown as a function of sample size. The areas under the curve (AUC) for the brain-behavior associations also are displayed.
| ABCD Study | Brain-behavior relationships for CBCL-externalizing | ||
|---|---|---|---|
|
| |||
| Standard | Motion-ordered | Bagging | |
| Low-motion White Youth | mean Rs [95% CI] | mean Rs [95% CI] | mean Rs [95% CI] |
| 25 | 0.097 [−0.29, 0.46] | 0.064 [−0.34, 0.49] | 0.071 [−0.32, 0.44] |
| 39 | 0.10 [−0.19, 0.41] | 0.086 [−0.22, 0.39] | 0.067 [−0.26, 0.40] |
| 62 | 0.094 [−0.13, 0.33] | 0.063 [−0.20, 0.30] | 0.067 [−0.20, 0.30] |
| 97 | 0.092 [−0.099, 0.28] | 0.066 [−0.12, 0.25] | 0.068 [−0.12, 0.27] |
| 152 | 0.098 [−0.050, 0.25] | 0.072 [−0.078, 0.22] | 0.066 [−0.082, 0.22] |
| 238 | 0.095 [−0.033, 0.22] | 0.069 [−0.049, 0.18] | 0.073 [−0.042, 0.19] |
| 374 | 0.099 [0.007, 0.19] | 0.072 [−0.027, 0.16] | 0.070 [−0.023, 0.16] |
| 586 | 0.10 [0.031, 0.17] | 0.072 [−0.006, 0.14] | 0.070 [0.005, 0.15] |
| 920 | 0.098 [0.053, 0.14] | 0.070 [0.022, 0.12] | 0.070 [0.019, 0.12] |
| 1444 | 0.099 [0.068, 0.13] | 0.071 [0.038, 0.10] | 0.072 [0.041, 0.10] |
| 2266 | 0.099 [0.099, 0.099] | 0.071 [0.071, 0.071] | 0.071 [0.071, 0.072] |
| Area Under Curve (AUC) | 244.82 | 250.70 | 251.44 |
|
| |||
| Low-motion Black Youth | mean Rs [95% CI] | mean Rs [95% CI] | mean Rs [95% CI] |
| 25 | 0.055 [−0.35, 0.45] | 0.078 [−0.31, 0.48] | 0.039 [−0.36, 0.43] |
| 33 | 0.060 [−0.28, 0.38] | 0.063 [−0.30, 0.42] | 0.045 [−0.30, 0.39] |
| 44 | 0.056 [−0.23, 0.35] | 0.052 [−0.23, 0.36] | 0.050 [−0.22, 0.31] |
| 58 | 0.054 [−0.18, 0.27] | 0.056 [−0.18, 0.29] | 0.051 [−0.18, 0.28] |
| 77 | 0.048 [−0.15, 0.23] | 0.047 [−0.15, 0.26] | 0.046 [−0.16, 0.25] |
| 101 | 0.055 [−0.12, 0.22] | 0.055 [−0.10, 0.22] | 0.044 [−0.14, 0.22] |
| 134 | 0.061 [−0.065, 0.19] | 0.052 [−0.088, 0.17] | 0.053 [−0.094, 0.19] |
| 177 | 0.059 [−0.048, 0.16] | 0.055 [−0.055, 0.16] | 0.050 [−0.055, 0.17] |
| 234 | 0.063 [−0.023, 0.15] | 0.053 [−0.030, 0.14] | 0.053 [−0.026, 0.14] |
| 310 | 0.059 [0.007, 0.11] | 0.051 [−0.004, 0.11] | 0.052 [−0.005, 0.10] |
| 410 | 0.059 [0.059, 0.059] | 0.054 [0.054, 0.054] | 0.051 [0.049, 0.053] |
| Area Under Curve (AUC) | 82.69 | 84.96 | 85.52 |
|
| |||
| Low-motion Hispanic Youth | mean Rs [95% CI] | mean Rs [95% CI] | mean Rs [95% CI] |
| 25 | 0.061 [−0.34, 0.43] | 0.065 [−0.33, 0.45] | 0.053 [−0.37, 0.45] |
| 35 | 0.079 [−0.22, 0.43] | 0.058 [−0.29, 0.38] | 0.065 [−0.25, 0.37] |
| 48 | 0.089 [−0.20, 0.34] | 0.066 [−0.18, 0.35] | 0.073 [−0.21, 0.35] |
| 67 | 0.081 [−0.15, 0.31] | 0.067 [−0.17, 0.31] | 0.073 [−0.16, 0.32] |
| 93 | 0.086 [−0.091, 0.27] | 0.065 [−0.11, 0.27] | 0.067 [−0.11, 0.26] |
| 129 | 0.083 [−0.063, 0.23] | 0.064 [−0.082, 0.22] | 0.065 [−0.085, 0.22] |
| 179 | 0.082 [−0.036, 0.21] | 0.063 [−0.056, 0.19] | 0.073 [−0.039, 0.19] |
| 249 | 0.077 [−0.016, 0.16] | 0.064 [−0.034, 0.15] | 0.069 [−0.015, 0.16] |
| 345 | 0.082 [0.007, 0.14] | 0.068 [−0.008, 0.14] | 0.068 [−0.008, 0.14] |
| 480 | 0.082 [0.037, 0.13] | 0.066 [0.021, 0.11] | 0.067 [0.018, 0.11] |
| 666 | 0.082 [0.082, 0.082] | 0.066 [0.066, 0.066] | 0.066 [0.065, 0.068] |
| Area Under Curve (AUC) | 113.75 | 117.00 | 115.94 |