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. 2025 Aug 4;17(8):e89335. doi: 10.7759/cureus.89335

Table 4. Comparison of dose received by normal structures in various studies.

Studies Techniques Brainstem, maximum dose (Gy) Optic chiasm, maximum dose (Gy) Optic nerve, maximum dose (Gy) Lens, maximum dose (Gy) Whole brain, mean dose (Gy) Conformity index  Homogeneity index
Shaffer et al., 2010 [18] Intensity modulated radiotherapy 55.6 52.2 Ipsilateral: 51.9; Contralateral: 41.9 Right lens: 8.7; Left lens: 8.6 22.7 1.16 1.15
Volumetric arc radiotherapy 55.6 52.5 Ipsilateral: 51.9; Contralateral: 35.2 Right lens: 6.1; Left lens: 6.1 24.7 1.18 1.15
Chan et al., 2003 [19] Intensity modulated radiotherapy 59 49 24 3.1 32 - -
Volumetric arc radiotherapy 58 43 23 2.9 27 - -
Thibouw et al., 2018 [20] Three-dimensional conformal radiotherapy 53.2 40 17.25 - 27.8 1.53 -
Intensity modulated radiotherapy 54.8 52.9 34.2 - 25.7 1.25 -
Ibis et al., 2018 [21] Three-dimensional conformal radiotherapy 54.6 44 44.2 4.9 32.3 2.3 -
Volumetric arc radiotherapy 47.2 41.7 Contralateral: 23.9; Ipsilateral: 37.3 Contralateral: 6.2; Ipsilateral: 6.8 23.8 1 -
Our study Three-dimensional conformal radiotherapy 45.54 33.87 Right optic nerve: 27.5; Left optic nerve: 25 Right lens: 3.62; Left lens: 3.92 27.6 0.95 1.06
Volumetric arc radiotherapy 44.99 37.35 Right optic nerve: 25.57; Left optic nerve: 22.68 Right lens: 5.06; Left lens: 4.79 26.88 0.98 1.06