Table 3.
Top five drugs and their durations for selected indications in children
| Indication Group | Rank | Antibiotic | n | % of Indication Total |
Drug Concordance | Duration Days, Mean (Median) | Recommended Duration Days | Reference |
|---|---|---|---|---|---|---|---|---|
| Otitis Media (n = 37,814) | 1 | Amoxicillin | 23,923 | 63% | Concordant | 9.04 (7) | 5–10 | 22 |
| 2 | Cefdinir | 6,071 | 16% | Concordant | 9.40 (7) | 5–10 | 22 | |
| 3 | AMX-CLV | 4,495 | 12% | Concordant | 9.27 (7) | 5–10 | 22 | |
| 4 | Azithromycin | 2,566 | 7% | Discordant | 8.97 (5) | |||
| 5 | Cephalexin | 175 | .5% | Discordant | 7.44 (7) | |||
| Group A Streptococci (n = 17,721) | 1 | Amoxicillin | 11,945 | 67% | Concordant | 9.17 (7) | 10 | 16 |
| 2 | Azithromycin | 1,813 | 10% | Concordant | 6.33 (5) | 5 | 16 | |
| 3 | Cephalexin | 1,064 | 6% | Concordant | 8.76 (7) | 10 | 16 | |
| 4 | AMX-CLV | 1,034 | 6% | Discordant | 8.76 (7) | |||
| 5 | Cefdinir | 870 | 5% | Discordant | 8.32 (7) | |||
| Sinusitis (n = 9,149) | 1 | Amoxicillin | 2,531 | 28% | Concordant | 9.77 (7) | 5–10 | 20 |
| 2 | AMX-CLV | 2,060 | 23% | Concordant | 9.06 (7) | 10–14 | 19 | |
| 3 | Azithromycin | 879 | 10% | Discordant | 4.28 (5) | |||
| 4 | Cefdinir | 736 | 8% | Concordant | 10.59 (10) | 10–14 | 19 | |
| 5 | Doxycycline | 237 | 3% | Discordant | 8.00 (10) | |||
| Urinary Tract Infection (n = 4,147) | 1 | Cephalexin | 1,632 | 39% | Concordant | 6.84 (7) | 5–10 | 23 |
| 2 | SMZ-TMP | 973 | 23% | Concordant | 7.19 (7) | 3 | 17 | |
| 3 | Cefdinir | 496 | 12% | Concordant | 6.07 (7) | 3–7 | 17 | |
| 4 | Nitrofurantoin | 436 | 11% | Concordant | 5.95 (5) | 5–7 | 17 | |
| 5 | Amoxicillin | 197 | 5% | Discordant | 6.87 (7) | |||
| Cellulitis (n = 3,861) | 1 | Cephalexin | 1,694 | 44% | Concordant | 7.21 (7) | 5 | 15 |
| 2 | AMX-CLV | 761 | 20% | Discordant | 7.40 (7) | |||
| 3 | SMZ-TMP | 555 | 14% | Discordant | 7.69 (7) | |||
| 4 | Clindamycin | 142 | 4% | Concordant | 9.86 (7) | 5 | 15 | |
| 5 | Doxycycline | 140 | 4% | Discordant | 6.73 (7) | 5 | 15 |
Abbreviation: AMX-CLV, amoxicillin-clavulanate; SMZ-TMP, sulfamethoxazole-trimethoprim.