TABLE 2.

Clinical Outcomes

Clinical Outcomes	Derivation Cohort (Pediatric Acute Lung Injury Cohort)			Validation Cohort (Coagulation and Fibrinolysis in Pediatric Insulin Titration Trial Cohort)
Mortality	n	OR (95% CI)	p	n	OR (95% CI)	p
Univariate	214	1.88 (1.24–2.84)	0.003	251	1.49 (1.02–2.19)	0.04
Multivariable (age, sex, race, OI)	214	1.71 (1.12–2.62)	0.014	251	1.47 (0.97–2.23)	0.06
Multiple organ failure/Pediatric Logistic Organ Dysfunction	n	Coefficient (95% CI)	p	n	Coefficient (95% CI)	p
Univariate	214	2.78 (1.16–4.4)	0.001	248	1.62 (0.25–3.0)	0.02
Multivariable (age, sex, race, OI)	214	2.45 (0.78–4.13)	0.004	248	1.32 (0.05–2.6)	0.04
Ventilator-free days	n	Coefficient (95% CI)	p	n	Coefficient (95% CI)	p
Univariate	201	−1.63 (−3.1 to −0.17)	0.03	251	−1.77 (−2.95 to −0.59)	0.003
Multivariable (age, sex, race, OI)	201	−1.25 (−2.74 to 0.25)	0.1	251	−1.32 (−2.72 to −0.074)	0.06
ICU length of stay	n	Coefficient (95% CI)	p	n	Coefficient (95% CI)	p
Univariate	214	−0.96 (−4.3 to 2.38)	0.57	217	4.32 (2.0–6.65)	< 0.001
Multivariable (age, sex, race, OI)	214	−1.08 (−5.37 to 3.2)	0.62	217	4.23 (2.1–6.37)	< 0.0001

OI = oxygenation index, OR = odds ratio.