Table 4.

Univariate and multivariate analysis of risk factors associated with adenocarcinoma and dysplasia.

Adenocarcinoma
Univariate					Multivariate
	B	P-value	Exp(B)	95% CI	B	P-value	Exp(B)	95% CI
Age	0.039	.009	1.040		0.023	.160	1.023
Gender	0.220	.621	1.246
Gallstones	−1.434	.003	0.238	0.09–0.61	−1.168	.036	0.311	0.10–0.91
Acute cholecystitis	−15.502	.998	0.000
Low-grade dysplasia	−15.512	.997	0.000
High-grade dysplasia	6.191	.000	488.162	120.58–1976.20	5.733	.000	308.980	63.49–1984.71
Chronic cholecystitis	−2.368	.000	0.094	0.04–0.22	−1.677	.001	0.187	0.05–0.45
Polyps	2.520	.001	12.434	2.83–54.53	2.940	.000	18.923	4.12–92.51
Intestinal metaplasia	4.370	.000	79.036	8.47–737.07	3.887	.005	48.767	4.74–831.10
Pyloric Metaplasia	−15.566	.993	0.000
Constant						.00	0.01

Dysplasia
	Univariate				Multivariate
	B	P-value	Exp(B)	95% CI	B	P-value	Exp(B)	95% CI
	0.020	.001	1.021	1.09–1.03	0.023	.000	1.023	1.01–1.03
Age	0.064	.730	1.066	0.65–1.35
Gender	−0.103	.919	0.902	0.12–6.56
Polyps	2.923	.000	18.601	12.94–26.72	2.936	.000	18.848	13.06–27.19
Intestinal metaplasia	0.514	.065	1.671	0.96–288	0.205	.490	1.227	0.68–2.19
Pyloric metaplasia	−17.325	.997	0.000	0.00–0.00	−17.325	.997	0.000
Acute cholecystitis	−0.124	.627	0.883	0.53–1.45
Chronic cholecystitis	−0.088	.618	0.915	0.64–1.29
Gallstones
Constant						.00	0.04

The bold values indicate statistical significance at P < .05.