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. Author manuscript; available in PMC: 2025 Aug 6.
Published in final edited form as: Clin Cancer Res. 2025 Sep 2;31(17):3652–3661. doi: 10.1158/1078-0432.CCR-24-3803

Table 3:

Response to fulvestrant, palbociclib and erdafitinib combination according to FGFR1-4 amplification status

All patients FGFR1-4 amp FGFR1-4 non-amp
Total number of cases 35 29 6

Evaluable for efficacy 31 27 4
Best Overall Response
 CR 0 0 0
 PR 3 (10%) 2 (8%) 1 (25%)
 SD 17 (55%) 16 (59%) 1 (25%)
 PD 11 (35%) 9 (33%) 2 (50%)
 Non evaluable 4 2 2
Clinical Benefit Rate at 6 months 23% 22% 25%
Duration of overall response range 18-112 w 18-39 w 122 w
Median progression free survival (range) 12 w (5-144w) 12 w (6-55w) 13 w (5-144w)