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Table 2.

Anesthetic and analgesic protocol followed in the included studies.

Study Anesthesia Peripheral anesthesia Basic analgesia protocol Anesthetic cocktail
T C T C
Aliste et al. (9) SA PENG SFIB PCA (morphine bolus = 1 mg; lockout interval = 8 min), oral acetaminophen (1 g, q6h) and ketoprofen (100 mg, q8h) during 48 h 20 mL of adrenalized levobupivacaine 0.50% 40 mL of adrenalized levobupivacaine 0.25%
Bravo et al. (27) SA PENG PAI PCA (morphine bolus = 1 mg; lockout interval = 8 min), oral acetaminophen (1 g, q6h) and ketoprofen (100 mg, q8h) during 48 h 20 mL of adrenalized bupivacaine 0.50% 60 mL of adrenalized bupivacaine 0.25%
Carella et al. (28) SA PENG SFIB Intravenous paracetamol (1 g) at the end of the surgery, oral paracetamol (1 g, q6h) and etoricoxib (60 mg, qd), and PCA (0.2% morphine) after surgery 20 mL of ropivacaine 0.75% 40 mL of ropivacaine 0.375%
Choi et al. (29) GA PENG SFIB PCA (fentany l7 μg/kg), oral celecoxib (200 mg, q12h), and intravenous acetaminophen (1 g, q12h) 20 mL of ropivacaine 0.2% with epinephrine 1:200,000 30 mL of ropivacaine 0.2% with epinephrine 1:200,000
Domagalska et al. (14) SA PENG Sham Intravenous acetaminophen (1 g, q6h), metamizole (1 g, q6h), and oral ketorolac (50 mg, q12h) 20 mL of ropivacaine 0.5% 20 mL of NaCl 0.9%
Et et al. (12) SA PENG PAI Intravenous paracetamol (1 g, q8h) and oral diclofenac (50 mg, 25 mg ≥75 years, q8h) 20 mL of bupivacaine 0.5% 30 mL of 5% bupivacaine with 30 mL of saline
Iglesias et al. (30) SA PENG PAI Oral paracetamol (500 mg, q8h), etoricoxib (60 mg, q12h), and gabapentin (300 mg, qn) 20 mL of 0.25% bupivacaine with epinephrine 80 mL of morphine 10 mg, ketorolac 60 mg, and bupivacaine 0.25% with epinephrine
Kukreja et al. (15) SA PENG Blank Oral paracetamol and celecoxib 25 mL of bupivacaine 0.5% None
Vamshi et al. (11) GA PENG SFIB PCA (1 mg morphine bolus with a lockout time of 10 min with a maximal dose of 20 mg/4 h), and 1 g intravenous paracetamol (1 g) at 6 h after surgery 30 mL of bupivacaine 0.25% with clonidine 1 μg/kg 30 mL of bupivacaine 0.25% with clonidine 1 μg/kg
Ye et al. (13) GA PENG PAI Oral celecoxib (200 mg, q12h) 20 mL of ropivacaine 0.5% with 1:200,000 adrenaline 30 mL of ropivacaine 0.33% with 1:200,000 adrenaline
Zheng et al. (5) SA PENG PAI PCA (fentanyl 1,500 μg and ramosetron 0.6 mg), and oral naproxen (VIMOVO® 500/20 mg) 30 mL of ropivacaine 0.5% 20 mL of ropivacaine 0.75%, ketorolac 60 mg, and epinephrine 1 g

C, control group; GA, general anesthesia; PAI, the periarticular anesthetic infiltration; PCA, patient-controlled analgesia; PENG, the pericapsular nerve group block; PLA, posterolateral approach; SA, spinal anesthesia; SFIB, the suprainguinal fascia iliaca block; T, treatment group.