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. 2025 Aug 7;15:28846. doi: 10.1038/s41598-025-14002-2

Table 2.

Cox regression model.

Categories Model 1 Model 2 Model 3
HR (95% CI) P-value P for trend HR (95% CI) P-value P for trend HR (95% CI) P-value P for trend
180 days mortality
 GPR(Per 10 U) 2.96 (2.50 ~ 3.49)  < 0.001 1.79 (1.45 ~ 2.21)  < 0.001 1.71 (1.36 ~ 2.17)  < 0.001
 Quartile  < 0.001  < 0.001  < 0.001
  Q1 (N = 471) Reference Reference Reference
  Q2 (N = 471) 0.79 (0.63 ~ 0.99) 0.048 0.84 (0.66 ~ 1.06) 0.138 1.01 (0.80 ~ 1.28) 0.942
  Q3 (N = 471) 1.37 (1.12 ~ 1.68) 0.002 1.14 (0.93 ~ 1.40) 0.204 1.40 (1.13 ~ 1.74) 0.002
  Q4 (N = 472) 2.50 (2.07 ~ 3.02)  < 0.001 1.63 (1.34 ~ 1.98)  < 0.001 1.87 (1.51 ~ 2.31)  < 0.001
1 year mortality
 GPR(Per 10 U) 2.96 (2.51 ~ 3.49)  < 0.001 1.81 (1.46 ~ 2.24)  < 0.001 1.70 (1.34 ~ 2.15)  < 0.001
 Quartile  < 0.001  < 0.001  < 0.001
  Q1 (N = 471) Reference Reference Reference
  Q2 (N = 471) 0.82 (0.66 ~ 1.01) 0.058 0.86 (0.70 ~ 1.06) 0.167 1.02 (0.83 ~ 1.27) 0.824
  Q3 (N = 471) 1.33 (1.10 ~ 1.60) 0.003 1.12 (0.93 ~ 1.35) 0.249 1.34 (1.10 ~ 1.63) 0.004
  Q4 (N = 472) 2.34 (1.97 ~ 2.78)  < 0.001 1.52 (1.27 ~ 1.82)  < 0.001 1.70 (1.40 ~ 2.07)  < 0.001

Model 1 was unadjusted.

Model 2 was adjusted for age, gender, BMI, race, tobacco use status, and the presence of hypertension, HF, stroke, ARF, CKD, diabetes, cardiogenic shock, as well as revascularization status.

Model 3 included additional adjustments for potassium, chloride, GLU, AG, WBC, RBC, PLT, Hb, RDW, HCT, PT,APTT, BUN, and Cr, based on Model 2.