Table 3.
Time-to-onset analysis of semaglutide-related depressive disorders signals using the Weibull distribution test in the FAERS database.
PT | Time-to-onset (days) |
Weibull distribution |
Failure type | |||||
---|---|---|---|---|---|---|---|---|
Scale parameter |
Shape parameter |
|||||||
N | Median (IQR) | Min–Max | α | 95% CI | β | 95% CI | ||
Depression | 492 | 21.0 (2.0, 69.0) | 0–1116 | 74.67 | 57.70–96.62 | 0.71 | 0.62–0.80 | Early failure |
Depression suicidal | 29 | 0.0 (0.0, 15.5) | 0–111 | 46.85 | 13.75–159.65 | 0.98 | 0.40–2.39 | Random failure |
Note: Text in bold signifies that the signal is categorized as an important medical events (IMEs). IMEs are developed and updated by European Medicines Agency (EMA).
IQR, Interquartile Range.