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. 2024 Nov 14;2:imag-2-00372. doi: 10.1162/imag_a_00372

Table 7.

Comparing between various vertex-based analysis toolboxes/software.

VertexWiseR QDECR ( Lamballais & Muetzel, 2021 ) BrainStat ( Larivière et al., 2023 ) FreeSurfer ( Fischl, 2012 ) CAT12 ( Gaser et al., 2024 ) TFCE_mediation ( Lett et al., 2017 )
Operating systems (outside of dockers/virtual machines) Windows, Linux, MacOS Linux, MacOS Windows, Linux, MacOS Linux, MacOS Windows, Linux, MacOS Linux, MacOS
Environment R R Python/MATLAB CLE MATLAB GUI CLE
Preprocess raw data No No No Yes Yes No
Reads surface data from preprocessed output directories Yes
(FreeSurfer, HCP pipeline, HippUnfold, fMRIprep)
Yes
(FreeSurfer)
No Yes
(FreeSurfer)
Yes
(CAT12)
Yes
(FreeSurfer, CIVET)
Concatenates all subjects’ data into a single portable file Yes
(.rds format)
No No Yes
(.mgh format)
No Yes
(.mgh format)
Surface supported fsaverage5, fsaverage6,fsLR32k, CIT168 All fsaverage All fsaverage,
fsLR32k, CIVET
All fsaverage fsLR32k All fsaverage,
CIVET
Cluster thresholding procedure RFT, TFCE MCS RFT MCS TFCE, FWE, FDR TFCE
Supported statistical models Linear,
Mixed-effects
Linear Linear,
Mixed-effects
Linear,
Mixed-effects
Linear,
Flexible factorial
Linear,
Mediation
Extract atlas-based ROIs Yes No No Yes Yes No
Meta-analytic decoding Yes No Yes No No No

Note. CLE = command line environment; GUI = graphical user interface; RFT = random field theory; FDR = false discovery rate; TFCE = threshold-free cluster enhancement; MCS = Monte Carlo simulation; FWE = family wise error.