表 1.
肾透明细胞癌与非透明细胞癌伴静脉癌栓患者的临床病理特征比较
Baseline clinical and tumor characteristics of clear cell and non-clear cell renal cell carcinoma patients with venous tumor thrombus
| Variables | Total | ccRCC | nccRCC | P |
| Data were M (IQR). BMI, body mass index; IQR, interquartile range; ccRCC, clear cell renal cell carcinoma; nccRCC, non-clear cell renal cell carcinoma; ASA, American Society of Anesthesiologists. | ||||
| Number of patients | 437 (100.0) | 366 (83.8) | 71 (16.2) | |
| Age/years | 58 (14) | 59 (8) | 55 (18) | 0.010 |
| Gender | 0.191 | |||
| Male | 317 (72.5) | 270 (73.8) | 47 (66.2) | |
| Female | 120 (27.5) | 96 (26.2) | 24 (33.8) | |
| BMI/(kg/m2) | 24.0 (4.7) | 24.0 (5.0) | 24.1 (4.1) | 0.734 |
| Tumor laterality | 0.194 | |||
| Left | 167 (38.2) | 135 (36.9) | 32 (45.1) | |
| Right | 270 (61.8) | 231 (63.1) | 39 (54.9) | |
| Histologic type | ||||
| Clear cell | 366 (83.8) | 366 (100) | - | |
| Papillary | 38 (8.7) | - | 38 (53.5) | |
| Chromophobe | 2 (0.5) | - | 2 (2.8) | |
| Unclassified | 11 (2.5) | - | 11 (15.5) | |
| Molecularly defined | 19 (4.3) | - | 19 (26.8) | |
| Collecting duct | 1 (0.2) | - | 1 (1.4) | |
| Tumor diameter/cm | 8.6 (3.8) | 8.4 (3.9) | 9.5 (4.1) | 0.025 |
| N | 0.034 | |||
| N0 | 177 (40.5) | 158 (43.2) | 20 (29.4) | |
| N1 | 260 (59.5) | 208 (56.8) | 48 (70.6) | |
| M | 0.074 | |||
| M0 | 315 (72.1) | 270 (73.8) | 45 (63.4) | |
| M1 | 122 (27.9) | 96 (26.2) | 26 (37.6) | |
| Tumor thrombus grading | < 0.001 | |||
| 0 | 112 (25.6) | 97 (26.5) | 15 (21.1) | |
| 1 | 73 (16.7) | 61 (16.7) | 12 (16.9) | |
| 2 | 182 (41.6) | 154 (42.1) | 28 (39.4) | |
| 3 | 37 (8.5) | 25 (6.8) | 12 (16.9) | |
| 4 | 33 (7.6) | 29 (7.9) | 4 (5.7) | |
| Sarcomatoid/rhabdoid differentiation | 0.118 | |||
| Absent | 374 (85.6) | 309 (84.4) | 65 (91.5) | |
| Present | 63 (14.4) | 57 (15.6) | 6 (8.5) | |
| Pathologic grade | 0.010 | |||
| 1-2 | 157 (35.9) | 141 (38.5) | 16 (22.5) | |
| 3-4 | 280 (64.1) | 225 (61.5) | 55 (77.5) | |
| ASA grade | 0.233 | |||
| 1-2 | 367 (84.0%) | 304 (83.1) | 63 (88.7) | |
| 3-4 | 70 (16.0) | 62 (16.9) | 8 (11.3) | |