Table 1.
Demographics, baseline characteristics, glucose and insulin (per protocol set PPS and full analysis set FAS)
| Parameter | PPS | FAS | |
|---|---|---|---|
| n | N (female/male) | 12 (4/8) | 16 (5/11) |
| Age (years) | Mean (SD) | 64.7 (3.4) | 65.4 (3.2) |
| Median (Min, Max) | 64.5 (59, 70) | 66.0 (59, 70) | |
| Weight (kg) | Mean (SD) | 94.4 (13.0) | 92.9 (11.8) |
| Median (Min, Max) | 93.1 (79, 126) | 91.6 (79, 126) | |
| Body mass index (kg/m2) | Mean (SD) | 30.7 (3.8) | 30.5 (3.9) |
| Median (Min, Max) | 29.8 (25, 37) | 29.8 (25, 37) | |
| Lean body weight (kg) | Mean (SD) | 62.0 (12.2) | 61.6 (11.0) |
| Median (Min, Max) | 64.5 (44, 79) | 64.5 (44, 79) | |
| Fasting glucose (mmol/L) | Visit 2 Mean (SD) | 7.4 (1.0) | 7.3 (0.9) |
| Visit 3 Mean (SD) | 7.6 (1.6) | 7.5 (1.4) | |
| Fasting insulin (mU/L) | Visit 2 Mean (SD) | 13.2 (6.7) | 12.7 (6.3) |
| Visit 3 Mean (SD) | 13.2 (6.3) | 13.5 (5.5) | |
| Glucose during M-value determination (mmol/L) | Visit 2 Mean (SD) | 5.5 (0.3) | 5.4 (0.3) |
| Visit 3 Mean (SD) | 5.5 (0.3) | 5.5 (0.3) | |
| Insulin during M-value determination (mU/L) | Visit 2 Mean (SD) | 149.2 (39.7) | 139.8 (43.8) |
| Visit 3 Mean (SD) | 158.8 (37.0) | 149.3 (44.3) |