Abstract
Purpose
Preventing the progression of occupational low back pain (LBP) is a critical occupational safety and health concern, alongside reducing its incidence. Manual handling of heavy loads may increase LBP severity. This study investigates the impact of lifting and carrying weights on LBP severity in affected workers.
Methods
A total of 2418 cases of acute occupational LBP, each resulting in more than four days of absence from work, were analyzed. These cases, reported as industrial accidents in Japan 2018–2019, were categorized into four weight-handling groups: < 10, 10–20, 20–30, and ≥ 30 kg. LBP severity was defined based on the duration of work absence, as determined by a physician’s diagnosis at the onset, and was categorized into four groups: 4–7, 8–14, 15–30, and ≥ 31 days. Multinomial logistic regression analysis was conducted to assess the relationship between handling weights and absence duration.
Results
The odds ratio (OR) for absence of ≥ 31 days compared with 4–7 days increased with heavier handling weights. Notably, workers handling 30 kg or more weights had a significantly higher OR than those under 10 kg (OR: 1.75; 95% CI: 1.11–2.77). The ORs for absence of 8–14 and 15–30 days compared with 4–7 days showed no significant association with handling weight.
Conclusion
Lifting and carrying heavier loads were associated with increased LBP severity and prolonged work absences. Minimizing manual handling loads may be a practical strategy to reduce the severity of acute occupational LBP and prevent prolonged work absences.
Supplementary Information
The online version contains supplementary material available at 10.1007/s00420-025-02148-5.
Keywords: Absenteeism, Low back pain, Manual labor, Severity of illness index
Introduction
Preventing the progression of occupational low back pain (LBP) is a significant occupational safety and health challenge, equally as critical as preventing its occurrence (Khadour et al. 2024; Saravanan et al. 2021; Shigetoh et al. 2024; Wu et al. 2024). Addressing this issue facilitates the early return of employees to the workplace, thereby reducing workers’ compensation costs and maintaining labor productivity.
In Japan, occupational LBP accounts for approximately 60% of all occupational diseases (Ministry of Health, Labour and Welfare 2004–2023), with 16% of cases involving severe LBP that results in more than one month of absence from work (Iwakiri et al. 2022). Additionally, nearly a quarter of occupational LBP cases are attributed to manual handling of heavy objects, such as lifting and carrying (National Institute of Occupational Safety and Health, Japan 2021). As a preventive measure, the maximum allowable manual handling load is regulated at 40% of body weight for men and 24% for women, according to guidelines issued by the Ministry of Health, Labour and Welfare (2013). However, these national standards do not fully comply with ISO 11228–1 (International Organization for Standardization 2021).
The relationship between handling loads and LBP remains unclear (Bakker et al. 2009; Kwon et al. 2011; Wai et al. 2010). However, manual handling of heavy objects is recognized as a risk factor for LBP (Bláfoss et al. 2020, 2024; Brauer et al. 2020; Holtermann et al. 2013). Increased strain on lumbar intervertebral discs has been reported in association with heavier manual handling loads (Mondal et al. 2019; Schäfer et al. 2023; Schmid et al. 2020; Wilke et al. 1999). Consequently, heavier manual handling loads may increase the risk of severe occupational LBP. However, recent occupational health studies have not specifically investigated the relationship between manual handling weight and the severity of occupational LBP.
In Japan, worker accidents must be reported to the Ministry of Health, Labour and Welfare through the Reports of Worker Casualties. These reports categorize incidents into two groups: absences of four or more days and absences of fewer than four days. The former is considered more severe and requires details such as the number of absent days, the circumstances surrounding the incident, and its causes. The reported absence duration is based on the recuperation period determined by a physician’s diagnosis, with longer absences indicating greater injury severity. Reports on manual lifting and carrying accidents include descriptions of work conditions, such as handling weight and working posture, documented in free-form text and diagrams.
Therefore, this study aimed to clarify the impact of manual handling weight during lifting and carrying on the severity of occupational LBP, as indicated by the number of absent days from work.
Methods
Research design
This study analyzed 10,208 cases of compensable occupational LBP documented in the Reports of Worker Casualties. These cases involved four or more days of absence and were reported as industrial accidents by the Ministry of Health, Labour and Welfare in Japan between 2018 and 2019. The cases analyzed represented 60.1% (N = 10,208) of all 16,994 occupational disease cases. Of these, 99.4% (N = 10,148) were classified as acute (accident-related) LBP and 0.6% (N = 60) as chronic (non-accident-related) LBP (Iwakiri et al. 2022). This study focused on acute LBP, which constituted the majority of cases and was primarily caused by back strain while lifting and lowering heavy loads.
The dataset was refined by excluding 20 duplicate cases, 335 cases with insufficient information, 2623 cases with unspecified handling weights, 4802 cases involving activities other than lifting and carrying, and 10 cases of chronic occupational LBP (Fig. 1). As a result, the final dataset comprised 2418 cases, which were categorized into four handling weight groups.
Fig. 1.
Flowchart illustrating the selection process in this study
This study was performed in line with the principles of the Declaration of Helsinki and adopted an opt-out approach, enabling individuals to decline participation and publication without providing a reason. Ethical approval was obtained from the Ethics Board of the National Institute of Occupational Safety and Health (Registration ID: 2021N07). The study was supported by funding from the institute (Grant N-P03-01).
Reports of worker casualties
The Reports of Worker Casualties for cases involving ≥ 4 days of absence included victim details, such as gender, age, years of experience, duration of work absence, industry type, and circumstances and causes of the accident. Years of experience were defined as the total years of employment in the worker’s current occupation. Work absence was defined as the expected recovery period determined by a physician’s diagnosis (Katoh et al. 2019). The duration of work absence, as determined by physician diagnosis, was used to define LBP severity and was classified into four categories: 4–7, 8–14, 15–30, and ≥ 31 days. The circumstances and causes of accidents were recorded in free-form text and diagrams, from which information on handling weights and working postures was extracted.
Lifting and carrying operations were defined as tasks involving lifting, lowering, and carrying objects weighing > 0 kg, while activities such as pushing, pulling, and rolling objects were excluded. For tasks performed by multiple workers, the total weight was divided by the number of workers to estimate the weight handled per individual. Handling weights were categorized into four groups: < 10 kg (N = 439), 10–20 kg (N = 898), 20–30 kg (N = 611), and ≥ 30 kg (N = 470; Fig. 1). Working postures were categorized as either proper posture (without improper movements) or improper postures, which included twisting, bending forward, squatting, and other unnatural positions.
Data analysis
The chi-squared (χ2) test was used to compare four weight groups: < 10, 10–20, 20–30, and ≥ 30 kg. Multinomial logistic regression analysis was performed to examine the association between handling weights and the number of absent days from work. Odds ratios (ORs) with 95% confidence intervals (95% CIs) were calculated for the model.
The dependent variable was the number of absent days from work, categorized into three groups: 8–14, 15–30, and ≥ 31 days, with 4–7 days as the reference category. The independent variable was handling weight, categorized into 10–20, 20–30, and ≥ 30 kg, with < 10 kg as the reference category. The model was adjusted for sex, age, industry type, and working posture, all treated as categorical variables.
The variance inflation factor for the independent and adjusted variables was < 1.2, confirming the absence of multicollinearity. All statistical analyses were conducted using IBM SPSS Statistics version 27, with a statistical significance set at p < 0.05 for all tests.
Results
The mean age of the injured workers was 40.8 yr. (standard deviation [SD]: 12.6 yr.; range: 16–90 yr.). Their mean years of experience was 5.2 yr. (SD: 7.1 yr.; range: 0–50 yr.), and their mean number of absent days from work was 22.5 days (SD: 28.3 days; range: 4–364 days).
Working handling heavier weights were more likely to be male, work in proper postures, and be employed in the construction and transportation industries compared with those handling lighter weights (Table 1). Regarding absent days from work, those handling heavier weights were less likely to have absences of 4–7 days and more likely to have absences of ≥ 31 days. No significant differences in age or years of experience were observed among the weight groups.
Table 1.
Number of occupational low back pain cases by worker basic information and handling weight category (N = 10,208)
| N (%) | Handling weight | p value | |||
|---|---|---|---|---|---|
| < 10 kg (N = 439) | 10–20 kg (N = 898) | 20–30 kg (N = 611) | ≥ 30 kg (N = 470) | ||
| Sex | < 0.001 | ||||
| Male | 220 (50.1) | 514 (57.2) | 470 (76.9) | 427 (90.9) | |
| Female | 219 (49.9) | 384 (42.8) | 141 (23.1) | 43 (9.1) | |
| Age (years) | 0.802 | ||||
| < 30 | 95 (21.6) | 184 (20.5) | 132 (21.6) | 97 (20.6) | |
| 30–39 | 107 (24.4) | 238 (26.5) | 161 (26.4) | 144 (30.6) | |
| 40–49 | 127 (28.9) | 257 (28.6) | 166 (27.2) | 118 (25.1) | |
| 50–59 | 66 (15.0) | 140 (15.6) | 94 (15.4) | 76 (16.2) | |
| ≥ 60 | 44 (10.0) | 79 (8.8) | 58 (9.5) | 35 (7.4) | |
| Years of experience | 0.429 | ||||
| < 1 | 135 (30.8) | 272 (30.3) | 174 (28.5) | 138 (29.7) | |
| 1–3 | 110 (25.1) | 207 (23.1) | 139 (22.7) | 85 (18.1) | |
| 3–5 | 61 (13.9) | 113 (12.6) | 79 (12.9) | 70 (14.9) | |
| 5–10 | 66 (15.0) | 144 (16.0) | 98 (16.0) | 84 (17.9) | |
| ≥ 10 | 67 (15.3) | 162 (18.0) | 121 (19.8) | 93 (19.8) | |
| Industry | < 0.001 | ||||
| Manufacturing | 103 (23.5) | 252 (28.1) | 188 (30.8) | 119 (25.3) | |
| Construction | 12 (2.7) | 27 (3.0) | 41 (6.7) | 48 (10.2) | |
| Transportation | 43 (9.8) | 124 (13.8) | 100 (16.4) | 104 (22.1) | |
| Forwarder | 13 (3.0) | 36 (4.0) | 18 (2.9) | 12 (2.6) | |
| Commerce | 173 (39.4) | 271 (30.2) | 140 (22.9) | 74 (15.7) | |
| Hospitality and entertainment industry | 39 (8.9) | 62 (6.9) | 31 (5.1) | 28 (6.0) | |
| Cleaning and slaughter industry | 16 (3.6) | 20 (2.2) | 19 (3.1) | 20 (4.3) | |
| Other businesses | 40 (9.1) | 106 (11.8) | 74 (12.1) | 65 (13.8) | |
| Working posture | < 0.001 | ||||
| Proper posture | 240 (54.7) | 578 (64.4) | 408 (66.8) | 334 (71.1) | |
| Twisting posture | 63 (14.4) | 96 (10.7) | 55 (9.0) | 37 (7.9) | |
| Forward-bending position | 34 (7.7) | 77 (8.6) | 36 (5.9) | 20 (4.3) | |
| A half-crouching position | 41 (9.3) | 52 (5.8) | 41 (6.7) | 30 (6.4) | |
| Other postures | 61 (13.9) | 95 (10.6) | 71 (11.6) | 49 (10.4) | |
| Absent days from work | 0.034 | ||||
| 4–7 | 160 (36.4) | 303 (33.7) | 200 (32.7) | 144 (30.6) | |
| 8–14 | 128 (29.2) | 274 (30.5) | 155 (25.4) | 125 (26.6) | |
| 15–30 | 105 (23.9) | 211 (23.5) | 165 (27.0) | 120 (25.5) | |
| ≥ 31 | 46 (10.5) | 110 (12.2) | 91 (14.9) | 81 (17.2) | |
Multinomial logistic regression analysis indicated that the OR for absence of ≥ 31 days increased with heavier handling weights compared with 4–7 days, while no significant associations were found for absences of 8–14 or 15–30 days (Table 2). For absences of 31 days or more, workers handling weights of 30 kg or more had a significantly higher OR than those handling less than 10 kg (OR: 1.75; 95% CI: 1.11–2.77). Additionally, workers handling weights of 20–30 kg exhibited a tendency toward a higher OR than those handling less than 10 kg (OR: 1.51; 95% CI: 0.98–2.31). However, no significant difference in OR was observed between handling weights of 10–20 kg and less than 10 kg (OR: 1.28; 95% CI: 0.86–1.91).
Table 2.
Association of absent days from work with handling weights using multinomial logistic regression analysis
| Absent days for 8–14 days (ref 4–7 days) | Absent days for 15–30 days (ref 4–7 days) | Absent days for ≥ 31 days (ref 4–7 days) | |
|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Handling weight (kg) | |||
| < 10 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| 10–20 | 1.11 (0.83–1.48) | 1.05 (0.77–1.42) | 1.28 (0.86–1.91) |
| 20–30 | 0.92 (0.67–1.27) | 1.16 (0.83–1.61) | 1.51 (0.98–2.31) |
| ≥ 30 | 1.00 (0.71–1.43) | 1.10 (0.76–1.59) | 1.75 (1.11–2.77) |
| (Adjusted variables) | |||
| Sex | |||
| Male | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| Female | 0.95 (0.75–1.20) | 0.94 (0.73–1.21) | 0.87 (0.64–1.20) |
| Age (years) | |||
| < 30 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| 30–39 | 0.98 (0.73–1.31) | 0.94 (0.69–1.28) | 1.52 (1.01–2.28) |
| 40–49 | 1.10 (0.82–1.48) | 1.23 (0.91–1.67) | 1.51 (1.00–2.28) |
| 50–59 | 1.36 (0.97–1.92) | 1.49 (1.04–2.14) | 2.10 (1.33–3.32) |
| ≥ 60 | 1.29 (0.82–2.03) | 2.03 (1.31–3.17) | 4.43 (2.66–7.37) |
| Industry | |||
| Manufacturing | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| Construction | 1.14 (0.65–2.02) | 2.33 (1.40–3.88) | 2.24 (1.21–4.15) |
| Transportation | 1.08 (0.78–1.50) | 1.08 (0.77–1.52) | 1.50 (0.99–2.27) |
| Forwarder | 1.25 (0.71–2.19) | 1.05 (0.57–1.93) | 0.34 (0.10–1.14) |
| Commerce | 0.94 (0.71–1.25) | 0.82 (0.61–1.10) | 1.15 (0.79–1.66) |
| Hospitality and entertainment industry | 1.13 (0.71–1.80) | 1.42 (0.89–2.26) | 2.04 (1.18–3.54) |
| Cleaning and slaughter industry | 0.94 (0.49–1.80) | 1.19 (0.64–2.24) | 1.21 (0.56–2.61) |
| Other businesses | 1.51 (1.06–2.16) | 1.18 (0.81–1.73) | 1.52 (0.95–2.41) |
| Working posture | |||
| Proper posture | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| Twisting posture | 0.95 (0.68–1.34) | 0.76 (0.53–1.10) | 0.95 (0.61–1.46) |
| Forward-bending position | 0.69 (0.46–1.04) | 0.73 (0.48–1.12) | 0.65 (0.37–1.14) |
| A half-crouching position | 0.93 (0.61–1.41) | 1.05 (0.69–1.59) | 0.78 (0.45–1.38) |
| Other postures | 1.05 (0.75–1.46) | 1.05 (0.74–1.48) | 1.23 (0.82–1.86) |
95% CI: and present the OR first, followed by the 95% CI. 95% confidence interval; OR: odds ratio. Adjusted variables are sex, age, industry, and working posture
Discussion
This study examined the impact of handling weight during lifting and carrying on the severity of acute occupational LBP, as indicated by the duration of work absence. The findings demonstrated that handling weight was not associated with absences of ≤ 30 days but was associated with prolonged absences of ≥ 31 days, with the most pronounced impact observed for weights of ≥ 30 kg.
Although the precise mechanisms underlying acute LBP remain unclear, primary sources of pain are believed to include damage or inflammation of the intervertebral disk (Hyodo et al. 2005; Ohtori et al. 2015), facet joint (O’Neill et al. 2009), sacroiliac joint (Cohen 2005; Kaye et al. 2021), and muscle fascia (Brandl et al. 2022; Cozacov et al. 2022). Biomechanical research has demonstrated that increased manual load leads to higher compressive forces on the lumbar spine, which may aggravate damage to intervertebral discs, facet joints, sacroiliac joints, and associated muscle fascia (Mondal et al. 2019; Schäfer et al. 2023; Schmid et al. 2020; Wilke et al. 1999). Therefore, increased handling weight imposes greater stress on these structures, leading to more significant damage, which likely contributes to increased LBP severity and prolonged work absences.
This study found no significant relationship between handling weight and absence durations of 30 days or less. No standardized guidelines exist for determining the appropriate length of work absence, with clinicians typically making this decision in consultation with patients. Acute LBP, commonly referred to as a strained back, generally resolves within a few days to 4 weeks (Maher et al. 2017; Pengel et al. 2003), though in some cases, it may persist beyond a month (Itz et al. 2012; McIntosh and Hall 2011; Pfeiffer et al. 2024). The factors contributing to prolonged LBP remain unclear, but possible causes include herniated disks (Kotwicki et al. 2021), spinal canal stenosis (Lai et al. 2021), and osteoporosis (Casazza 2012), as well as psychological and psychosocial influences (Hallegraeff et al. 2012; Nieminen et al. 2021). While further research is needed to clarify these aspects, cases of LBP that resolve within one month may not be significantly affected by handling weight.
Among the variables adjusted in the multinomial logistic regression analysis, age, and industry type were significantly associated with prolonged work absences (≥ 31 days, reference group: 4–7 days). The OR for longer absences increased with age, with the highest risk observed among workers aged ≥ 60 yr, despite their typically lighter manual handling loads. Prior studies suggest that age-related degeneration of intervertebral discs and spinal musculature contributes to this vulnerability (Asai et al. 2020; Benoist 2003; Dallaway et al. 2020a, 2020b; Ferguson and Steffen 2003). Regarding industry type, elevated ORs were noted in the construction and hospitality and entertainment sectors compared with the manufacturing sector. Automation in manufacturing has reduced manual load handling, whereas construction work still involves frequent handling of heavy materials such as cement bags and steel plates. Similarly, in the hospitality and entertainment industry, workers often lift items like food and alcoholic beverages in confined spaces, and staff shortages make adequate rest difficult. Prolonged standing and repetitive lifting likely contribute to musculoskeletal strain, particularly among older workers. These findings suggest that older workers in these sectors who are involved in heavy lifting face an increased risk of developing severe LBP.
This study has several limitations. First, not all occupational LBP cases are reported as industrial accidents. The process of filing claims for occupational injuries is often time-consuming, leading some individuals to forgo reporting. Consequently, this study only reflects cases where claims were submitted. Second, missing weight data in some reports may have influenced the findings, as claims were accepted even when weight values were not provided. The absence of this data may indicate different trends, and the results of this study apply only to cases with reported weight values. Third, this study focused exclusively on acute LBP and did not consider chronic LBP, which requires separate analysis. Lastly, the recorded absence period may not always correspond to the actual duration of absence. A previous study reported that approximately 70% of workers experienced longer absences than officially recorded (Katoh et al. 2019). As a result, this study may have underestimated LBP severity. Further research is needed to address these limitations and enhance the comprehensiveness of the findings.
Although this study has certain limitations, it also has notable strengths. It covers occupational LBP cases eligible for compensation nationwide in Japan. Additionally, because workers with load-handling duties and short absences served as the reference group, identifying statistically significant differences was more challenging. Nevertheless, the significant association between heavier handling weights and prolonged absences of ≥ 31 days is a noteworthy finding.
Conclusion
Heavier lifting and carrying loads were associated with prolonged absences of ≥ 31 days but showed no significant relationship with absences of ≤ 30 days. This association was particularly pronounced for weights of ≥ 30 kg. Handling heavier manual loads is likely to exacerbate the severity of acute occupational LBP and result in extended work absences. Reducing load weights may help prevent the progression of acute LBP into more severe stages.
Supplementary Information
Below is the link to the electronic supplementary material.
Acknowledgements
The authors would like to thank Mrs. Yuko Nishimura for assistance with data entry and Dr. Ko Matsudaira for his valuable advice from a medical perspective.
Author contributions
All authors contributed to the study conception and design. Kazuyuki Iwakiri and Keiichi Miki collected the data. Kazuyuki Iwakiri analyzed the data and drafted the initial manuscript. Kazuyuki Iwakiri and Takeshi Sasaki interpreted the data. Takeshi Sasaki and Keiichi Miki critically reviewed the manuscript. All authors read and approved the final manuscript.
Funding
This study was funded by a grant from the National Institute of Occupational Safety and Health, Japan (Grant N-P03-01).
Data availability
Data will be available upon request.
Declarations
Conflict of interest
The authors declare no conflict of interest.
Ethical approval
This study was conducted using the principles of the Declaration of Helsinki and employed an opt-out approach, allowing individuals to decline participation and publication without providing a reason. Ethical approval was obtained from the Ethics Board of the National Institute of Occupational Safety and Health (Registration ID: 2021N07).
Footnotes
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
References
- Asai T, Sakuma E, Mizutani T, Ishizaka Y, Ori K, Ueki T (2020) Sex- and age-related differences in spinal degeneration: an anatomical and magnetic resonance imaging study of the human spine. Prog Rehabil Med 7:20220011. 10.2490/prm.20220011 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bakker EWP, Verhagen AP, van Trijffel E, Lucas C, Koes BW (2009) Spinal mechanical load as a risk factor for low back pain: a systematic review of prospective cohort studies. Spine 34:E281-293. 10.1097/BRS.0b013e318195b257 [DOI] [PubMed] [Google Scholar]
- Benoist M (2003) Natural history of the aging spine. Eur Spine J 12:S86–S89. 10.1007/s00586-003-0593-0 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bláfoss R, Skovlund SV, López-Bueno R, Calatayud J, Sundstrup E, Andersen LL (2020) Is hard physical work in the early working life associated with back pain later in life? A cross-sectional study among 5700 older workers. BMJ Open 10:e040158. 10.1136/bmjopen-2020-040158 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bláfoss R, Aagaard P, Clausen T, Andersen LL (2024) Association of objectively measured lifting load with low-back pain, stress, and fatigue: a prospective cohort study. Scand J Work Environ Health 50:11–21. 10.5271/sjweh.4127 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brandl A, Egner C, Reer R, Schmidt T, Schleip R (2022) Associations between deformation of the thoracolumbar fascia and activation of the erector spinae and multifidus muscle in patients with acute low back pain and healthy controls: a matched pair case-control study. Life 12:1735. 10.3390/life12111735 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brauer C, Mikkelsen S, Pedersen EB, Møller KL, Simonsen EB, Koblauch H, Alkjær T, Helweg-Larsen K, Thygesen LC (2020) Occupational lifting predicts hospital admission due to low back pain in a cohort of airport baggage handlers. Int Arch Occup Environ Health 93:111–122. 10.1007/s00420-019-01470-z [DOI] [PMC free article] [PubMed] [Google Scholar]
- Casazza BA (2012) Diagnosis and treatment of acute low back pain. Am Fam Physician 85:343–50 [PubMed] [Google Scholar]
- Cohen SP (2005) Sacroiliac joint pain: a comprehensive review of anatomy, diagnosis, and treatment. Anesth Analg 101:1440–1453. 10.1213/01.ANE.0000180831.60169.EA [DOI] [PubMed] [Google Scholar]
- Cozacov R, Minerbi A, Haddad M, Vulfsons S (2022) Differential sensitization of muscle versus fascia in individuals with low back pain. Bioengineering 9:440. 10.3390/bioengineering9090440 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dallaway A, Hattersley J, Diokno M, Tallis J, Renshaw D, Wilson A, Wayte S, Weedall A, Duncan M (2020a) Age-related degeneration of lumbar muscle morphology in healthy younger versus older men. Aging Male 23:1583–1597. 10.1080/13685538.2021.1878130 [DOI] [PubMed] [Google Scholar]
- Dallaway A, Kite C, Griffen C, Duncan M, Tallis J, Renshaw D, Hattersley J (2020b) Age-related degeneration of the lumbar paravertebral muscles: systematic review and three-level meta-regression. Exp Gerontol 133:110856. 10.1016/j.exger.2020.110856 [DOI] [PubMed] [Google Scholar]
- Ferguson SJ, Steffen T (2003) Biomechanics of the aging spine. Eur Spine J 12:S97–S103. 10.1007/s00586-003-0621-0 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hallegraeff JM, Krijnen WP, van der Schans CP, de Greef MHG (2012) Expectations about recovery from acute non-specific low back pain predict absence from usual work due to chronic low back pain: a systematic review. J Physiother 58:165–172. 10.1016/S1836-9553(12)70107-8 [DOI] [PubMed] [Google Scholar]
- Holtermann A, Clausen T, Aust B, Mortensen OS, Andersen LL (2013) Risk for low back pain from different frequencies, load mass and trunk postures of lifting and carrying among female healthcare workers. Int Arch Occup Environ Health 86:463–470. 10.1007/s00420-012-0781-5 [DOI] [PubMed] [Google Scholar]
- Hyodo H, Sato T, Sasaki H, Tanaka Y (2005) Discogenic pain in acute nonspecific low-back pain. Eur Spine J 14:573–577. 10.1007/s00586-004-0844-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
- International Organization for Standardization (2021) ISO 11228–1 Ergonomics–manual handling–part 1: lifting, lowering and carrying. ISO, Geneva [Google Scholar]
- Itz CJ, Geurts JW, van Kleef M, Nelemans P (2012) Clinical course of non-specific low back pain: a systematic review of prospective cohort studies set in primary care. Eur J Pain 17:5–15. 10.1002/j.1532-2149.2012.00170.x [DOI] [PubMed] [Google Scholar]
- Iwakiri K, Sasaki T, Miki K (2022) Occupational low back pain in reports of workers’ casualties between 2018 and 2019 (in Japanese). Sangyo Eiseigaku Zasshi 64:354–366 [DOI] [PubMed] [Google Scholar]
- Katoh Y, Ota A, Yatsuya H (2019) Differences between expected and actual length of sick leave attributable to occupational accidents (in Japanese). J Occup Safety Health 12:173–179. 10.2486/josh.JOSH-2019-0009-CHO [Google Scholar]
- Kaye AD, Edinoff AN, Scoon L, Youn S, Farrell KJ, Kaye AJ, Shah RJ, Cornett EM, Chami AA, Dixon BM, Alvarado MA, Viswanath O, Urits I, Calodney AK (2021) Novel interventional techniques for chronic pain with minimally invasive arthrodesis of the sacroiliac joint: (INSITE, iFuse, Tricor, Rialto, and others). Rheumatol Ther 8:1061–1072. 10.1007/s40744-021-00350-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Khadour FA, Khadour YA, Alhatem W, Albarroush D, Dao X (2024) Risk factors associated with pain severity in Syrian patients with non-specific low back pain. BMC Musculoskelet Disord 25:687. 10.1186/s12891-024-07828-w [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kotwicki T, Rubczak S, Glowka P (2021) Three-dimensional reconstruction of intervertebral disc based on magnetic resonance imaging in patients with acute low back pain. Stud Health Technol Inform 280:63–65. 10.3233/SHTI210436 [DOI] [PubMed] [Google Scholar]
- Kwon BK, Roffey DM, Bishop PB, Dagenais S, Wai EK (2011) Systematic review: occupational physical activity and low back pain. Occup Med 61:541–548. 10.1093/occmed/kqr092 [DOI] [PubMed] [Google Scholar]
- Ministry of Health, Labour and Welfare (2013) Guidelines on the prevention of lumbago in the workplace (in Japanese). https://www.mhlw.go.jp/stf/houdou/2r98520000034et4-att/2r98520000034mtc_1.pdf
- Lai MKL, Cheung PWH, Samartzis D, Karppinen J, Cheung KMC, Cheung JPY (2021) Clinical implications of lumbar developmental spinal stenosis on back pain, radicular leg pain, and disability. Bone Joint J 103-B:131–140. 10.1302/0301-620X.103B1.BJJ-2020-1186.R2 [DOI] [PubMed] [Google Scholar]
- Maher C, Underwood M, Buchbinder R (2017) Non-specific low back pain. Lancet 389:736–747. 10.1016/S0140-6736(16)30970-9 [DOI] [PubMed] [Google Scholar]
- McIntosh G, Hall H (2011) Low back pain (acute). BMJ Clin Evid 9:2011–1102 [PMC free article] [PubMed] [Google Scholar]
- Ministry of Health, Labour and Welfare (2004–2023) The Survey on the occurrence of occupational diseases (in Japanese). https://www.mhlw.go.jp/stf/newpage_09976.html
- Mondal K, Majumdar D, Pal MS, Sahrawat TR, Kumar B (2019) Association of manual weight lifting tasks with low back pain: a pilot study. J Clin Diagn Res 13:LC10–LC15. 10.7860/JCDR/2019/39691.12569 [Google Scholar]
- National Institute of Safety and Health, Japan (2021) The occurrence of occupational low back pain reported in the reports of worker casualties from 2018 to 2019 (in Japanese). https://www.jniosh.johas.go.jp/publication/doc/houkoku/2021_05/lowerbackpain_h30-r01.pdf
- Nieminen LK, Pyysalo LM, Kankaanpää MJ (2021) Prognostic factors for pain chronicity in low back pain: a systematic review. Pain Rep 6:e919. 10.1097/PR9.0000000000000919 [DOI] [PMC free article] [PubMed] [Google Scholar]
- O’Neill S, Graven-Nielsen T, Manniche C, Arendt-Nielsen L (2009) Ultrasound guided, painful electrical stimulation of lumbar facet joint structures: an experimental model of acute low back pain. Pain 144:76–83. 10.1016/j.pain.2009.03.014 [DOI] [PubMed] [Google Scholar]
- Ohtori S, Inoue G, Miyagi M, Takahashi K (2015) Pathomechanisms of discogenic low back pain in humans and animal models. Spine J 15:1347–1355. 10.1016/j.spinee.2013.07.490 [DOI] [PubMed] [Google Scholar]
- Pengel LH, Herbert RD, Maher CG, Refshauge KM (2003) Acute low back pain: systematic review of its prognosis. BMJ 2003:327–323. 10.1136/bmj.327.7410.323 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pfeiffer F, Luomajoki H, Meichtry A, Boendermaker SH (2024) The course of acute low back pain: a community-based inception cohort study. Pain Rep 9:e1152. 10.1097/PR9.0000000000001152 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Saravanan A, Bajaj P, Mathews HL, Tell D, Starkweather A, Janusek L (2021) Social support is inversely associated with sleep disturbance, inflammation, and pain severity in chronic low back pain. Nurs Res 70:425–432. 10.1097/NNR.0000000000000543 [DOI] [PubMed] [Google Scholar]
- Schäfer R, Trompeter K, Fett D, Heinrich K, Funken J, Willwacher S, Brüggemann GP, Platen P (2023) The mechanical loading of the spine in physical activities. Eur Spine J 32:2991–3001. 10.1007/s00586-023-07733-1 [DOI] [PubMed] [Google Scholar]
- Schmid S, Burkhart KA, Allaire BT, Grindle D, Bassani T, Galbusera F, Anderson DE (2020) Spinal compressive forces in adolescent idiopathic scoliosis with and without carrying loads: a musculoskeletal modeling study. Front Bioeng Biotechnol 8:159. 10.3389/fbioe.2020.00159 [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shigetoh H, Abiko T, Ohyama M, Sakata E, Murata S (2024) Subgroup characteristics in care workers with low back pain: cluster analysis-based severity of central sensitivity syndromes and low back pain. Eur Spine J 33:1447–1454. 10.1007/s00586-024-08143-7 [DOI] [PubMed] [Google Scholar]
- Wai EK, Roffey DM, Bishop P, Kwon BK, Dagenais S (2010) Causal assessment of occupational lifting and low back pain: results of a systematic review. Spine J 10:554–566. 10.1016/j.spinee.2010.03.033 [DOI] [PubMed] [Google Scholar]
- Wilke HJ, Neef P, Caimi M, Hoogland T, Claes LE (1999) New in vivo measurements of pressures in the intervertebral disc in daily life. Spine 24:755–762. 10.1097/00007632-199904150-00005 [DOI] [PubMed] [Google Scholar]
- Wu Y, Wulf Hanson S, Culbreth G, Purcell C, Brooks P, Kopec J, March L, Woolf AD, Pasovic M, Hamilton E, Santomauro D, Vos T (2024) Assessing the impact of health-care access on the severity of low back pain by country: a case study within the GBD framework. Lancet Rheumatol 6:e598–e606. 10.1016/S2665-9913(24)00151-6 [DOI] [PMC free article] [PubMed] [Google Scholar]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Supplementary Materials
Data Availability Statement
Data will be available upon request.

