Table 2. Demographic and clinical characteristics of patients with HIV/AIDS coinfected with TE under different immune statuses.
| Variable | <50 cells/µL (n=24) | 50–100 cells/µL (n=7) | >100 cells/µL (n=10) | F/H | P value | η²/V |
|---|---|---|---|---|---|---|
| Age (years) | 36.4±11.5 | 38.4±10.2 | 40.3±11.3 | 0.436 | 0.650 | 0.022 |
| Gender (male) | 23 (95.8) | 6 (85.7) | 8 (80.0) | 2.661 | 0.242 | 0.232 |
| Laboratory findings | ||||||
| Leukocyte count (×109/L) | 4.60±2.64 | 4.51±1.81 | 4.46±2.40 | 0.096 | 0.908 | 0.005 |
| Neutrophil ratio >0.7 | 12 (50.0) | 2 (28.6) | 2 (20.0) | 2.877 | 0.248 | 0.273 |
| CD8+ T-cell count | 5.047 | 0.041 | 0.414 | |||
| ≤200 cells/µL | 8 (33.3) | 0 | 0 | |||
| >200 cells/µL | 16 (66.7) | 7 (100.0) | 10 (100.0) | |||
| Cerebrospinal fluid | ||||||
| Leukocyte count (×106/L) | 6.6±3.0 | 5.6±1.8 | 6.7±4.7 | 1.345 | 0.528 | 0.069 |
| Protein (g/L) | 0.77±0.63 | 0.84±0.41 | 0.33±0.16 | 4.669 | 0.015 | 0.197 |
| Glucose (g/L) | 2.89±0.63 | 2.91±0.32 | 2.99±0.80 | 0.087 | 0.958 | 0.005 |
| Chloride (mmol/L) | 123.0±5.4 | 126.0±3.1 | 124.3±3.8 | 1.164 | 0.323 | 0.058 |
| Imaging findings | ||||||
| Number | ||||||
| Single (n=7) | 2 (8.3) | 2 (28.6) | 3 (30.0) | 3.473 | 0.144 | 0.217 |
| Multiple (n=34) | ||||||
| 2–5 (n=19) | 12 (50.0) | 2 (28.6) | 5 (50.0) | 1.597 | 0.519 | 0.162 |
| >5 (n=15) | 10 (41.7) | 3 (42.9) | 2 (20.0) | 1.578 | 0.598 | 0.196 |
| Distribution | ||||||
| Corticomedullary junction | 88 (69.3) | 30 (71.4) | 27 (79.4) | 1.346 | 0.510 | 0.081 |
| Thalamus-basal ganglia | 21 (16.5) | 10 (23.8) | 5 (14.7) | 1.401 | 0.496 | 0.083 |
| Cerebellum and brainstem | 18 (14.2) | 2 (4.8) | 2 (5.9) | 3.434 | 0.201 | 0.139 |
| Morphology | ||||||
| Ring-like | 65 (51.2) | 18 (42.9) | 13 (38.2) | 2.221 | 0.329 | 0.105 |
| Nodular | 41 (32.3) | 20 (47.6) | 18 (52.9) | 6.502 | 0.039 | 0.179 |
| Target sign | 4 (3.1) | 2 (4.8) | 5 (14.7) | 5.915 | 0.040 | 0.186 |
| Size (mm) | 9.8 (7.4–15.4) | 8.8 (6.7–10.9) | 8.7 (5.5–13.1) | 6.337 | 0.042 | 0.158 |
| Time of HIV diagnosis (days) | 30 (10.5–60) | 60 (20–240) | 60 (14–656.3) | 1.761 | 0.415 | 0.044 |
| Hospitalization time (days) | 30.8±13.8 | 33.6±19.3 | 27±7.4 | 0.506 | 0.607 | 0.026 |
| Outcome | 20 (83.3) | 6 (85.7) | 9 (90.0) | 0.267 | 0.875 | 0.078 |
Data are presented as the mean ± SD, n (%), or the median (IQR), as appropriate. AIDS, acquired immunodeficiency syndrome; CD8+ T-cell, CD8-positive T lymphocyte; HIV, human immunodeficiency virus; IQR, interquartile range; SD, standard deviation; TE, toxoplasmic encephalitis.