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. Author manuscript; available in PMC: 2026 Feb 10.
Published in final edited form as: Dev Neurosci. 2025 Feb 10;47(6):458–467. doi: 10.1159/000544063

Fig. 2.

Fig. 2.

Impact of hypoxic-ischemic (HI) injury and genotype on microglial counts by sex. Post-natal day 9–11 mice underwent unilateral carotid artery ligation followed by exposure to 8% oxygen for 25 min. Tissue was stained for Ionized Ca+2-binding adapter protein 1 (Iba-1), which was normalized by tissue area analyzed. If non-normally distributed, data underwent Box-Cox transformation and then analyzed by two-way ANOVA with post-hoc Tukey’s test. Visualized data is before transformation. A) Hemispheric Iba-1+ counts in males after HI vs. sham by genotype. B) Hemispheric Iba-1+ counts in females after HI vs. sham by genotype. C) Hippocampal Iba-1+ counts in males after HI vs. sham by genotype. D) Hippocampal Iba-1+ counts in females after HI vs. sham by genotype. Iba-1 = ionized calcium-binding adaptor molecule; WT = wild-type; Het = heterozygote; KO = knockout; HI = hypoxia-ischemia. NS=non-significant, *= P<0.05, **=P<0.01.