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. 2025 Jul 25;14(7):4071–4079. doi: 10.21037/tcr-2024-2359

Table 2. Comparison of ultrasound imaging characteristics between HER-2 negative and positive groups.

Image characteristics HER-2 negative group (n=31) HER-2 positive group (n=39) χ2 score P value
Size 8.5 0.004*
   <20 mm 22 14
   ≥20 mm 9 25
Shape 4.28 0.04*
   Regular 8 3
   Irregular 23 36
Edge 7.56 0.006*
   Clear 18 10
   Spiculated 13 29
Aspect ratio 0.154 0.69
   <1 26 34
   ≥1 5 5
Stiff ring sign 3.52 0.06
   Yes 9 20
   No 22 19
Calcification sign 10.88 0.001*
   Yes 10 28
   No 21 11

Data are expressed as number. *, statistically significant. HER-2, human epidermal growth factor receptor-2.