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. 2025 Jul 25;14(7):4071–4079. doi: 10.21037/tcr-2024-2359

Table 5. Comparison of using tumor elastic score, size, calcification status and combined parameters in determining HER-2 status of breast cancer.

Tumor parameter Cut-off value (kPa) Sensitivity (%) Specificity (%) Area under ROC curve
Emax 79.75 76.9 54.8 0.672
Size – 61.4 71 0.675
Calcification – 71.8 67.7 0.698
Emax + size – 82.1 61.3 0.719
Emax + calcification – 84.6 61.3 0.784
Size + calcification – 94.4 48.4 0.780
Emax + size + calcification – 66.7 83.9 0.800

Emax, maximum elastic modulus; HER-2, human epidermal growth factor receptor-2; ROC, receiver operating characteristic.