Skip to main content
[Preprint]. 2025 Aug 15:2025.07.09.663954. Originally published 2025 Jul 14. [Version 2] doi: 10.1101/2025.07.09.663954

Figure 5. No changes in ET intrinsic excitability after NE.

Figure 5.

(A) Average ET Rinput 1d and 7d after SE (black) or NE (red) (1d SE: 21 cells/6 mice; 1d NE: 21 cells/5 mice; 7d SE: 20 cells/5 mice; 7d NE: 23 cells/6 mice).

(B) Average ET Vrest 1d and 7d after SE (black) or NE (red) (1d SE: 21 cells/6 mice; 1d NE: 21 cells/5 mice; 7d SE: 20 cells/5 mice; 7d NE: 23 cells/6 mice).

(C) Average ET AP width 1d and 7d after SE (black) or NE (red) (1d SE: 21 cells/6 mice; 1d NE: 21 cells/5 mice; 7d SE: 20 cells/5 mice; 7d NE: 23 cells/6 mice).

(D) Average ET AP threshold 1d and 7d after SE (black) or NE (red) (1d SE: 21 cells/6 mice; 1d NE: 21 cells/5 mice; 7d SE: 20 cells/5 mice; 7d NE: 23 cells/6 mice).

(E1, E2, G1, G2) Representative traces of ET firing in response to depolarizing current injection (50, 100, 200 pA), 1d SE (E1) vs. 1d NE (E2); and 7d SE (G1) vs. 7d NE (G2).

(F, H) Average firing frequency as a function of injected current amplitude, 1d SE vs. 1d NE (F), and 7d SE vs. 7d NE (H). Current injections from 25 to 350 pA with an increment of 25 pA. (1d SE: 21 cells/6 mice; 1d NE: 21 cells/5 mice; 7d SE: 20 cells/5 mice; 7d NE: 23 cells/6 mice).

Detailed statistical values are listed in Table 1.