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[Preprint]. 2025 Jul 19:2025.07.15.664935. [Version 1] doi: 10.1101/2025.07.15.664935

Figure 5: Theoretical prediction: Feedback-dependent modulation of functional connectivity.

Figure 5:

a, Feedback from V5 → V1 is stronger than feedback from V4 → V1, and V1 preferentially enhances communication with V5. b, Feedback from V4 → V1 is stronger than feedback from V5 → V1, and V1 preferentially enhances communication with V4. The plotted prediction performance is an average across different subsets of the source and target populations, and the shaded areas represent the standard error of the mean (SEM). These results demonstrate that top-down feedback can dynamically route information flow between cortical areas, i.e., modulating functional connectivity.