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. 2025 Jul 29;12:1559372. doi: 10.3389/fmed.2025.1559372

Table 4.

AUC, sensitivity, Youden indexmax, and threshold of ROC curve analysis.

Indicators AUC Sensitivity Youden’s Indexmax Threshold p-value
IL-17 (ng/L) 1.000 100% 1.000 25.540 <0.0001
IL-18 (ng/L) 0.966(0.940–0.992) 82.00% 0.820 89.485 <0.001
IL-25 (ng/L) 0.987(0.964–1.000) 96.70% 0.967 32.625 <0.001
EOS (%) 0.919(0.864–0.973) 82.80% 0.787 3.135 <0.001
IL-18 + IL-25 + EOS 0.996(0.989–1.000) 98.40% 0.984 113.395 <0.001

AUC, the area under the ROC curve; Youden’s index, sensitivity+specificity −1; threshold, The corresponding indicator value of Youden indexmax.