TABLE 1.
In vitro susceptibilities of 7,299 isolates of Candida spp. and 1,615 isolates of Cryptococcus neoformans to itraconazole
| Organism (no. of isolates tested) | Cumulative % at MIC (μg/ml): |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 0.03 | 0.06 | 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | |
| C. albicans (3,895) | 46 | 88 | 98 | 99 | 99 | 99 | 99 | 99 | 99 |
| C. glabrata (1,054) | 1 | 1 | 2 | 9 | 37 | 77 | 91 | 94 | 95 |
| C. parapsilosis (1,028) | 1 | 10 | 48 | 87 | 97 | 99 | 100 | ||
| C. tropicalis (839) | 7 | 25 | 61 | 90 | 99 | 99 | 99 | 99 | 99 |
| C. krusei (206) | 1 | 2 | 10 | 53 | 94 | 99 | 100 | ||
| C. guilliermondii (90) | 1 | 4 | 14 | 73 | 99 | 99 | 100 | ||
| C. lusitaniae (89) | 2 | 5 | 54 | 93 | 98 | 100 | |||
| C. kefyr (29) | 24 | 83 | 97 | 100 | |||||
| C. pelliculosa (28) | 4 | 32 | 68 | 100 | |||||
| C. rugosa (15) | 7 | 27 | 60 | 80 | 100 | ||||
| Candida spp. (26)a | 20 | 38 | 54 | 80 | 92 | 96 | 96 | 100 | |
| All Candida (7,299) | 25 | 51 | 68 | 80 | 88 | 96 | 99 | 99 | 99 |
| Cryptococcus neoformans (1,615) | 2 | 6 | 26 | 61 | 76 | 80 | 83 | 92 | 98 |