TABLE 2.

Sensitivity and specificity of dot immunobinding and Widal assays for diagnosis of typhoid fever

Comparison	Dot immunobinding (titer ≥ 20,000)					Widal test
	ST O-HSA		ST LPS		ST O (100 ng)	Widal H		Widal O
	100 ng	10 ng	100 ng	10 ng		≥1/80	≥1/160	≥1/80	≥1/160
Typhoid fever versus patient controls
Sensitivity (%)	70	30	95a	85a	40	77	74	71	63
Specificity (%)	91	97	95	95	100	68	86	41	73
Typhoid fever versus all controls
Sensitivity (%)	70	30	95a	85a	40	NDb	ND	ND	ND
Specificity (%)	95	97	97	97	100	ND	ND	ND	ND

^aSensitivity is significantly different from that with ST O (P < 0.05; Fisher's exact test).

^bND, not determined.