TABLE 2.
Age-dependent IgG seroprevalence against representative species- and genus-specific adenovirus antigens in 667 patients by immunoblot assay
| Age group (no. of sera) | No. (%) of sera positive with species-representing antigens
|
No. (%) of sera positive with genus- specific antigens
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Ad3pIXC[B] | Ad2pIX[C] | Ad8FiKn[D] | Ad41pIX[F] | Single speciesa | All pIXb | All antigensc | Ad41Fi | Ad41Fid alone | Hexon | |
| 0-3 mo (48) | 8 (16.7) | 17 (35.4) | 9 (18.8) | 19 (39.6) | 14 (29.2) | 27 (56.2) | 29 (60.4) | 37 (77.1) | 12 (25.0) | 46 (95.8) |
| 4-11 mo (65) | 3 (4.6) | 9 (13.8) | 7 (10.8) | 11 (16.9) | 11 (16.9) | 17 (26.2) | 20 (30.8) | 29 (44.6) | 14 (21.5) | 59 (90.8) |
| 1-4 yr (104) | 14 (13.5) | 58 (55.8) | 20 (19.2) | 38 (36.5) | 33 (31.7) | 65 (62.5) | 70 (67.3) | 80 (76.9) | 16 (15.4) | 104 (100) |
| 5-14 yr (126) | 19 (15.1) | 75 (59.5) | 37 (29.4) | 44 (34.9) | 43 (34.1) | 85 (67.5) | 95 (75.4) | 112 (88.9) | 26 (20.6) | 125 (99.2) |
| 15-29 yr (100) | 21 (21.0) | 45 (45.0) | 23 (23.0) | 32 (32.0) | 31 (31.0) | 62 (62.0) | 67 (67.0) | 89 (89.0) | 27 (27.0) | 100 (100) |
| 30-50 yr (100) | 17 (17.0) | 47 (47.0) | 30 (30.0) | 44 (44.0) | 40 (40.0) | 73 (73.0) | 82 (82.0) | 95 (95.0) | 14 (14.0) | 100 (100) |
| 51-65 yr (86) | 32 (37.2) | 35 (40.7) | 35 (40.7) | 44 (51.2) | 22 (25.6) | 63 (73.3) | 70 (81.4) | 78 (90.7) | 12 (14.0) | 86 (100) |
| >65 yr (38) | 6 (15.8) | 12 (31.6) | 15 (39.5) | 12 (31.6) | 14 (36.8) | 18 (47.4) | 25 (65.8) | 32 (84.2) | 7 (18.4) | 38 (100) |
| Total (667) | 120 (18.0) | 298 (44.7) | 176 (26.4) | 244 (36.6) | 208 (31.2) | 410 (61.5) | 458 (68.7) | 552 (82.8) | 128 (19.2) | 658 (98.8) |
a
Single positive reaction per serum with any species-representing antigen.
b
Single or multiple positive reactions per serum with the species-representing pIX antigens.
c
Single or multiple positive reactions per serum with the species-representing pIX and fiber knob antigens.
d
No reaction with species-representing antigens.