Table 3.
Subgroup Analysis of Multimodal 1064 nm Nd:YAG Laser Therapy for Melasma Based on MASI Scores [mean±SD, M(P25, P75)]
| Subgroup | Number (n) | Before Treatment | After the Third Treatment |
Difference (Pre - Post) |
p |
|---|---|---|---|---|---|
| Skin Type | |||||
| Type III | 18 | 13.18±5.63 | 5.42±2.87 | 7.76±3.57 | 0.196 |
| Type IV | 25 | 13.40(9.90,24.10) | 6.18±3.73 | 7.50(5.85,14.85) | |
| Age (years) | |||||
| ≤40 | 26 | 12.00(8.10,13.95) | 4.98±2.67 | 6.60(5.18,9.08) | 0.007 |
| >40 | 17 | 18.94±7.82 | 7.21±3.97 | 11.74±5.44 | |
| Duration (months) | |||||
| ≤12 | 32 | 12.90(8.55,17.75) | 5.67±3.34 | 6.75(5.70,11.45) | 0.450 |
| >12 | 11 | 16.33±7.81 | 6.43±3.61 | 9.90±4.96 | |
| Etiology | |||||
| Genetic | 7 | 9.99±3.36 | 3.10(2.40,7.20) | 5.77±1.83 | 0.039 |
| Pregnancy | 19 | 13.61±6.63 | 5.33±3.34 | 8.28±4.00 | |
| Excessive sun exposure | 9 | 18.38±7.86 | 6.31±2.78 | 12.07±6.19 | |
| Other factors | 8 | 18.93±8.09 | 8.06±4.16 | 10.86±5.46 |