Table 2.
Unadjusted bivariate models for IBD patients with anemia.
Unadjusted logistic models: OR (95%CI) | ||||
---|---|---|---|---|
Patient characteristics | Resolution of anemia | Hospitalization within 5 years | Steroid within 5 years | Surgery within 5 years |
Age (years) Mean (±SD) |
0.99(0.99–0.99) | 0.97(0.97–0.97) | 0.97(0.97–0.97) | 0.97(0.97–0.97) |
Gender Male Female |
Ref 1.31(1.21–1.43) |
Ref 1.23(1.15–1.33) |
Ref 1.52(1.40–1.65) |
Ref 0.81(0.60–1.09) |
Race White African American Others Unknown |
Ref 0.84(0.78–0.91) 0.89(0.74–1.08) 0.75(0.69–0.81) |
Ref 1.23(1.16–1.30) 1.08(0.93–1.26) 0.70(0.65–0.74) |
Ref 0.98(0.91–1.05) 1.19(0.99–1.42) 0.40(0.37–0.44) |
Ref 0.83(0.65–1.05) 0.69(0.35–1.33) 0.48(0.37–0.63) |
Ethnicity Non–Hispanic/Latino Hispanic/Latino Unknown |
Ref 1.00(0.88–1.13) 0.72(0.66–0.78) |
Ref 1.16(1.05–1.29) 0.71(0.67–0.76) |
Ref 1.32(1.18–1.49) 0.31(0.27–0.34) |
1.22(0.86–1.73) 0.49(0.36–0.66) |
Smoking status Current Former Never Unknown |
Ref 0.96(0.89–1.03) 1.05(0.97–1.12) 0.86(0.80–0.92) |
Ref 0.53(0.50–0.56) 0.60(0.56–0.63) 0.82(0.77–0.86) |
Ref 0.78(0.73–0.83) 0.80(0.75–0.86) 0.53(0.50–0.57) |
Ref 0.54(0.44–0.66) 0.55(0.45–0.68) 0.62(0.52–0.75) |
Comorbidity No Comorbidity 1–2 >=3 |
Ref 0.81(0.77–0.85) 0.48(0.45–0.52) |
Ref 1.05(1.01–1.10) 1.16(1.10–1.22) |
Ref 1.07(1.02–1.13) 1.07(1.01–1.14) |
Ref 0.89(0.76–1.04) 1.08(0.89–1.30) |
Encounters*2 Mean(±SD) |
0.99(0.99–0.99) | 1.01(1.01–1.02) | 1.01(1.01–1.01) | 1.01(1.01–1.01) |
Priority group 7–8 1–6 |
Ref 0.93(0.89–0.98) |
Ref 2.08(1.98–2.19) |
Ref 1.55(1.46–1.65) |
Ref 1.68(1.38–2.04) |
Region Pacific Continental Midwest North Atlantic Southeast |
Ref 1.12(1.04–1.22) 0.97(0.90–1.04) 1.00(0.93–1.07) 1.05(0.97–1.13) |
Ref 0.81(0.76–0.87) 0.81(0.77–0.86) 0.69(0.65–0.73) 0.78(0.73–0.83) |
Ref 0.94(0.87–1.02) 1.00(0.93–1.08) 0.85(0.79–0.91) 0.90(0.83–0.97) |
Ref 1.06(0.84–1.33) 0.95(0.77–1.17) 0.74(0.59–0.91) 0.56(0.44–0.72) |
Academic affiliation No Yes |
Ref 0.84(0.77–0.92) |
Ref 1.74(1.58–1.91) |
Ref 1.10(0.99–1.21) |
Ref 1.28(0.91–1.79) |
IBD type Crohn’s disease Ulcerative colitis Indeterminate |
Ref 1.13(1.08–1.18) 0.85(0.72–0.99) |
Ref 0.54(0.52–0.56) 1.03(0.91–1.17) |
Ref 0.81(0.77–0.85) 1.05(0.90–1.21) |
Ref 0.84(0.73–0.96) 1.42(0.96–2.09) |
Concomitant IBD medication*1 | ||||
ASA alone Biologics + immunomodulator All others |
Ref 0.83(0.75–0.93) 0.83(0.79–0.88) |
Ref 3.64(3.34–3.98) 1.14(1.09–1.19) |
Ref 6.74(6.12–7.41) 2.04(1.92–2.16) |
Ref 5.01(3.86–6.49) 1.93(1.59–2.34) |
*
1±3 months of Index Anemia;
*
2Within 1 year of Index IBD.