Table 3:
Adjusted multivariate logistic models for IBD patients with anemia
| Adjusted Logistic Models: OR (95%CI) | ||||
|---|---|---|---|---|
| Patient Characteristics | Resolution of Anemia | Hospitalization within 5 years | Steroid within 5 years | Surgery within 5 years |
| Age (years) Mean (±SD) Median(IQR) |
0.99(0.99–0.99) | 0.98(0.97–0.98) | 0.98(0.98–0.98) | 0.98(0.97–0.98) |
| Gender Male Female |
Ref 1.34(1.23–1.46) |
Ref 0.79(0.73–0.85) |
Ref 1.04(0.95–1.13) |
Ref 0.54(0.40–0.73) |
| Race White African American Others Unknown |
Ref 0.82(0.76–0.89) 0.87(0.72–1.06) 0.84(0.76–0.92) |
Ref 0.93(0.88–0.99) 0.91(0.77–1.07) 0.79(0.72–0.86) |
Ref 0.78(0.72–0.84) 1.03(0.85–1.23) 0.71(0.63–0.79) |
Ref 0.69(0.53–0.85) 0.57(0.29–1.11) 0.61(0.47–0.95) |
| Ethnicity Hispanic/Latino Non–Hispanic/Latino Unknown |
Ref 1.03(0.91–1.16) 0.79(0.71–0.88) |
Ref 0.98(0.88–1.09) 0.92(0.84–1.01) |
Ref 1.11(0.98–1.26) 0.46(0.40–0.52) |
Ref 1.02(0.72–1.47) 0.75(0.51–1.11) |
| Smoking Status Current Former Never Unknown |
Ref 0.90(0.84–0.97) 0.93(0.86–0.99) 0.81(0.76–0.87) |
Ref 0.83(0.78–0.89) 0.81(0.76–0.86) 1.19(1.12–1.26) |
Ref 1.13(1.05–1.22) 1.01(0.94–1.09) 0.73(0.68–0.78) |
Ref 0.77(0.62–0.96) 0.72(0.58–0.89) 0.86(0.71–1.04) |
| Comorbidity No Comorbidity 1–2 >=3 |
Ref 0.89(0.85–0.94) 0.60(0.56–0.65) |
Ref 1.10(1.05–1.16) 1.06(0.99–1.13) |
Ref 1.20(1.13–1.27) 1.07(0.99–1.15) |
Ref 0.90(0.76–1.07) 0.88(0.71–1.09) |
| Encounters*2 Mean(±SD) |
0.99(0.99–0.99) | 1.01(1.01–1.01) | 1.01(1.01–1.01) | 1.01(1.01–1.01) |
| Priority Group 7–8 1–6 |
Ref 1.05(0.99–1.11) |
Ref 1.47(1.39–1.55) |
Ref 1.08(1.01–1.15) |
Ref 1.08(0.89–1.32) |
| Region Pacific Continental Midwest North Atlantic Southeast |
Ref 1.07(0.99–1.16) 0.92(0.85–0.99) 0.95(0.89–1.02) 1.01(0.94–1.10) |
Ref 0.79(0.74–0.85) 0.89(0.84–0.95) 0.76(0.71–0.81) 0.80(0.75–0.85) |
Ref 0.94(0.86–1.02) 1.05(0.97–1.14) 0.90(0.83–0.97) 0.96(0.88–1.04) |
Ref 1.09(0.86–1.38) 1.03(0.83–1.27) 0.84(0.67–1.04) 0.61(0.47–0.79) |
| Academic Affiliation No Yes |
Ref 0.88(0.80–0.96) |
Ref 1.59(1.44–1.75) |
Ref 1.02(0.92–1.04) |
Ref 1.21(0.86–1.71) |
| IBD type Crohn’s disease Ulcerative Colitis Indeterminate |
Ref 1.13(1.08–1.18) 0.97(0.82–1.14) |
Ref 0.61(0.58–0.63) 0.92(0.81–1.04) |
Ref 0.95(0.90–0.99) 1.00(0.86–1.17) |
Ref 1.04(0.90–1.21) 1.30(0.87–1.92) |
| Concomitant IBD medication*1 | ||||
| ASA alone Biologics +/–Immunomodulator All others |
Ref 0.84(0.75–0.94) 0.87(0.83–0.92) |
Ref 1.91(1.73–2.09) 0.89(0.85–0.93) |
Ref 4.11(3.72–4.55) 1.77(1.66–1.88) |
Ref 2.76(2.10–3.63) 1.56(1.28–1.90) |
*
1±3 months of Index Anemia;
*
2Within 1 year of Index IBD.