FIG. 6.

The level of radiation-induced apoptosis is decreased in Ada2 mutants. Wing imaginal disks of wild-type (D), Ada2a (E), and Ada2b (F) L3 larvae were irradiated at 4,000 R, left to recover for 4 h, and dissected, and the disks were stained with acridine orange. Controls (A, B, and C) were treated similarly, but without irradiation. (Right panel) Average number of AO-stained cells per wing disk, as determined in three independent experiments, each involving 10 disks or more. Ada2b* indicates Ada2b homozygotes carrying the Ada2b⁺ transgene.