Table 2.
Base-case results
| RDN groups | Control groups | Differences | Relative risk | |
|---|---|---|---|---|
| Number of events | ||||
| CHD | 60 | 83 | -23 | 0.72 |
| AMI | 47 | 64 | -17 | 0.73 |
| HF | 21 | 30 | -9 | 0.70 |
| SCD | 13 | 18 | -5 | 0.72 |
| Stroke | 255 | 370 | -115 | 0.69 |
| IS | 132 | 191 | -60 | 0.69 |
| HS | 123 | 178 | -56 | 0.69 |
| TIA | 105 | 152 | -47 | 0.69 |
| ESRD | 13 | 19 | -6 | 0.68 |
| Cardiovascular, stroke, and renal event mortality | 116 | 164 | -48 | 0.71 |
| Discount rate at 5% | ||||
| Mean LYs | 14.27 | 13.95 | 0.32 | - |
| Mean QALYs | 13.27 | 12.90 | 0.37 | - |
| Mean costs per person ($) | ||||
| Mainland China | 17,260 | 10,170 | 7091 | - |
| Japan | 34,592 | 28,703 | 5889 | - |
| Thailand | 10,994 | 4099 | 6896 | - |
| ICER ($/QALY) | ||||
| Mainland China | 19,049 | |||
| Japan | 15,821 | |||
| Thailand | 18,525 | |||
| ICER ($/LY) | ||||
| Mainland China | 22,046 | |||
| Japan | 18,310 | |||
| Thailand | 21,410 | |||
| Discount rate at 3% | ||||
| Mean LYs | 17.47 | 17.02 | 0.45 | |
| Mean QALYs | 16.23 | 15.72 | 0.51 | |
| Mean costs per person ($) | ||||
| Mainland China | 19,586 | 12,722 | 6864 | |
| Japan | 41,542 | 37,953 | 3589 | |
| Thailand | 12,287 | 5190 | 7097 | |
| ICER ($/QALY) | ||||
| Mainland China | 15,254 | |||
| Japan | 7046 | |||
| Thailand | 13,932 | |||
| ICER ($/LY) | ||||
| Mainland China | 14,927 | |||
| Japan | 8013 | |||
| Thailand | 15,845 | |||
| Discount rate at 2% | ||||
| Mean LYs | 19.53 | 19.00 | 0.53 | |
| Mean QALYs | 18.13 | 17.53 | 0.60 | |
| Mean costs per person ($) | ||||
| Mainland China | 21,105 | 14,388 | 6717 | |
| Japan | 46,183 | 44,105 | 2079 | |
| Thailand | 13,117 | 5887 | 7230 | |
| ICER ($/QALY) | ||||
| Mainland China | 11,153 | |||
| Japan | 3451 | |||
| Thailand | 12,005 | |||
| ICER ($/LY) | ||||
| Mainland China | 12,674 | |||
| Japan | 3894 | |||
| Thailand | 13,544 | |||
AMI, acute myocardial infarction; CHD, coronary heart disease; ESRD, end-stage renal disease; HF, heart failure; HS, hemorrhagic stroke; ICER, incremental cost-effectiveness ratio; IS, ischemic stroke; LY: life year; SCD, sudden cardiac death; QALY, quality-adjusted life year; RDN, renal denervation; TIA, transient ischemic attacks