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. 2025 Jul 30;16:1614492. doi: 10.3389/fmicb.2025.1614492

Table 9.

Comparative ranking of pathways between Buchnera and other bacteria.

Pathway Rank in others Rank in Buchnera
Aerobic respiration I (cytochrome C) 1 175
Pyruvate fermentation to isobutanol (engineered) 2 11
Gondoate biosynthesis (anaerobic) 3 60
Mycolate biosynthesis 4 162
L-isoleucine biosynthesis II 5 6
Fatty acid elongation—saturated 6 61
L-isoleucine biosynthesis I (from threonine) 7 13
L-valine biosynthesis 8 12
Oleate biosynthesis IV (anaerobic) 9 54
Fatty acid beta-oxidation I 10 1
Cis-vaccenate biosynthesis 11 77
Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) 12 71
Stearate biosynthesis II (bacteria and plants) 13 89
TCA cycle I (prokaryotic) 14 3
(5Z)-dodec-5-enoate biosynthesis 15 39
Superpathway of fatty acid biosynthesis initiation (E. coli) 16 59
Superpathway of L-serine and glycine biosynthesis I 17 104
CDP-diacylglycerol biosynthesis II 18 42
CDP-diacylglycerol biosynthesis I 19 41
Pentose phosphate pathway (non-oxidative branch) 20 5
Superpathway of branched amino acid biosynthesis 21 14
Fatty acid salvage 22 196
Superpathway of phospholipid biosynthesis I (bacteria) 23 16
Superpathway of sulfate assimilation and cysteine biosynthesis 24 38
L-isoleucine biosynthesis III 25 19
Urate biosynthesis/inosine 5′-phosphate degradation 26 48
8-amino-7-oxononanoate biosynthesis I 27 88
Sulfate reduction I (assimilatory) 28 15
Peptidoglycan maturation (meso-diaminopimelate containing) 29 9
Superpathway of adenosine nucleotides de novo biosynthesis I 30 18