ADC |
Antibody–drug conjugate |
BsAb |
Bispecific antibody |
CTLA4 |
Cytotoxic T-lymphocyte-associated protein 4 |
DAR |
Drug–antibody ratio |
Dato-DXd |
Datopotamab Deruxtecan |
DLL3 |
Delta-like Ligand 3 |
EGFR |
Epidermal growth factor receptor |
HER2 |
Human epidermal growth factor receptor 2 |
HER3 |
Human epidermal growth factor receptor 3 |
HER3-DXd |
Patritumab-deruxtecan |
ICI |
Immune checkpoint inhibitor |
ILD |
Interstitial lung disease |
irAE |
Immune-related adverse event |
ITT |
Intention to treat |
LAG3 |
Lymphocyte-activation gene 3 |
NSCLC |
Non-small cell lung cancer |
ORR |
Objective response rate |
OS |
Overall survival |
PD1 |
Programmed cell death protein 1 |
PDL1 |
Programmed death-ligand 1 |
PFS |
Progression-free survival |
SCLC |
Small cell lung cancer |
SG |
Sacituzumab Govitecan |
TCR |
T-cell receptor |
TROP2 |
Trophoblast Cell Surface Antigen 2 |
T-DM1 |
Trastuzumab Emtansine |
T-DXd |
Trastuzumab Deruxtecan |
TIGIT |
T cell immunoreceptor with Ig and ITIM domains |
TKI |
Tyrosine Kinase Inhibitor |