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. 2025 Jul 25;26(15):7171. doi: 10.3390/ijms26157171
PKU Phenylketonuria
HPA Hyperphenylalaninemia
BH4-r-HPA Tetrahydrobiopterin-Responsive Hyperphenylalaninemia
CPKU Classical Phenylketonuria
Phe Phenylalanine
Tyr Tyrosine
Trp Tryptophan
Phe/Tyr Phenylalanine to Tyrosine ratio
BMI Body Mass Index
BW Body Weight
IQR Interquartile Range
SD Standard Deviation
LC-MS/MS Liquid Chromatography–Mass Spectrometry
Q-TOF Quadrupole Time-of-Flight
CE Collision Energy
DDA Data-Dependent Analysis
PCA Principal Component Analysis
PLS-DA Partial Least Squares Discriminant Analysis
OPLS-DA Orthogonal Partial Least Squares Discriminant Analysis
VIP Variable Importance in Projection
MS Mass Spectrometry
NMR Nuclear Magnetic Resonance
ESI Electrospray Ionization
QC Quality Control
TG Triglyceride
DG Diglyceride
PC Phosphatidylcholine
LPC Lysophosphatidylcholine
SM Sphingomyelin
PUFA Polyunsaturated Fatty Acids
AGE Advanced Glycation End Products
ARPs Amadori Rearrangement Products
HbA1c Hemoglobin A1c (glycosylated hemoglobin)
IRIS Infrared Ion Spectroscopy
MRM Multiple Reaction Monitoring
UHPLC Ultra-High-Performance Liquid Chromatography
v/v Volume/Volume
m/z Mass-to-Charge-Ratio