Fig. 1.

Age-standardised incidence rates (ASIRs) of intrahepatic cholangiocarcinoma (iCCA) in Sweden between 2011 and 2021. Panel (a) presents ASIRs of all-stage, early-stage and intermediate- or late-stage iCCA across the study period, while panels (b) and (c) present ASIRs for men and women, respectively. Panels (d–f) present ASIRs for individuals with high, medium, and low household income, respectively. Restricted cubic splines were used to fit lines representing changes in the all-stage and stage-specific ASIRs of iCCA during the study period for each individual panel (a–f).