| α4β2 nAChRs | Alpha-4 beta-2 neuronal nicotinic acetylcholine receptors |
| BD | Bipolar Disorder |
| BDNF | Brain-Derived Neurotrophic factor |
| C_max | Maximum Plasma Concentration |
| FDA | Food and Drug Administration |
| NMDA | N-methyl-D-aspartate receptors |
| NRT | Nicotine Replacement Therapy |
| OR | Odds Ratio |
| RCT | Randomized Controlled Trial |
| SAEs | Serious Adverse Events |
| SCZ | Schizophrenia |