TSC	Tuberous sclerosis complex
IL-1β	Interleukin-1β
KD	Knockdown
ROS	Reactive oxygen species
mTOR	Mammalian target of rapamycin (mTOR)
NLRP3	NOD-like receptor protein 3
ASC	Apoptosis-associated speck-like protein containing a CARD
Pro-Caspase 1	Precursor cysteinyl aspartate-specific proteinase 1
CKO	Conditional knockout
Rapa	Rapamycin
DEGs	Differentially expressed genes
GSEA	Gene set enrichment analysis
NES	Normalized enrichment score
FC	Fold change
WGCNA	Weighted gene co-expression network analysis
GAMNIs	Genes associated with microglial NLRP3 inflammasome
PPI	Protein–protein interaction
GO	Gene Ontology
MF	Molecular Function
CC	Cellular Component
BP	Biological Process
HMC3	Human microglia cell line
RT-qPCR	Real-time quantitative polymerase chain reaction
PBS	Phosphate-buffered saline
DHE	Dihydroethidium