Table A3.
COVID-19 severity in relation to demographics, comorbidities, days in hospital, max needs of FiO2% and outcome.
| Characteristics | Mild/Moderate (N = 36) |
Severe/Critical (N = 475) |
p-Value |
|---|---|---|---|
| Age | 65.5 [37.0, 95.0] | 68.0 [22.0, 99.0] | 0.865 MW |
| Gender | |||
| Male | 9 (25.0%) | 255 (53.7%) | 0.00165 x2 |
| Female | 27 (75.0%) | 220 (46.3%) | |
| FiO2 | |||
| Mean (SD) | 22.3% (2.7%) | 50.8% (22.8%) | <0.001 MW |
| Median [Min, Max] | 21% [21%, 28%] | 40% [21%, 100%] | |
| Comorbidities | |||
| CVS disease | 11 (30.6%) | 121 (25.5%) | 0.635 x2 |
| Arterial hypertension | 7 (19.4%) | 208 (43.8%) | 0.00742 x2 |
| Diabetes Mellitus | 4 (11.1%) | 93 (19.6%) | 0.304 x2 |
| Malignancy | 5 (13.9%) | 37 (7.8%) | 0.204 fx |
| Immunosuppression | 0 (0%) | 8 (1.7%) | 1 fx |
| COPD | 1 (2.8%) | 38 (8.0%) | 0.508 fx |
| Sleep Apnea | 0 (0%) | 6 (1.3%) | 1 fx |
| Bronchial Asthma | 0 (0%) | 23 (4.8%) | 0.395 fx |
| Chronic kidney Disease | 0 (0%) | 5 (1.1%) | 1 fx |
| Neurological Disease | 12 (33.3%) | 74 (15.6%) | 0.0119 x2 |
| Psychiatric Disease | 12 (33.3%) | 51 (10.7%) | <0.001 fx |
| Morbid obesity | 0 (0%) | 12 (2.5%) | 1 fx |
| Autoimmune Disease | 2 (5.6%) | 7 (1.5%) | 0.127 fx |
| ECOG 4 | 0 (0%) | 17 (3.6%) | 0.623 fx |
| Days in hospital | 14.5 [6.00, 48.0] | 15.0 [5.00, 72.0] | 0.646 MW |
| Outcome | |||
| Improvement | 36 (100%) | 390 (82.1%) | 0.0148 fx |
| Death | 0 (0%) | 74 (15.6%) | |
| Discharge with O2 support | 0 (0%) | 6 (1.3%) | |
| Death | 0 (0%) | 74 (15.6%) | 0.0197 x2 |
MW: Mann–Whitney U test, fx: Fisher exact test, x2: χ2 test.