Fig. 8.
NMR-based solution structure of epiberberine (yellow) in complex with the human Tel2G4. Epiberberine recruits the A3 residue at the 5′-end to form a ligand–base co-plane. Potential H-bonds are indicated by dashed lines.
NMR-based solution structure of epiberberine (yellow) in complex with the human Tel2G4. Epiberberine recruits the A3 residue at the 5′-end to form a ligand–base co-plane. Potential H-bonds are indicated by dashed lines.