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. 2025 Jul 30;26(15):7375. doi: 10.3390/ijms26157375

Figure 1.

Figure 1

Schematic illustration of MDS-related genes on chromosome 17. Names of all protein-coding (black) and select non-coding (gray) genes in the MDS locus and neighboring regions of human chromosome 17p13.3 are shown. Gene order was obtained from the Human Genome Project Ensemble Database and UCSC Genome Browser [53,54]. Please note that 50 “ENSG” non-coding RNAs were omitted for brevity. Deletions specific to each human-derived MDS cell line (GM09208, GM06097, and GM26025) and reported samples from MDS patients (arbitrarily labeled as MDS 1–3) are denoted by lines with gene names at the boundaries. Base pairs with a question mark denote the uncertainty of the exact deletion. The dotted lines denote additional sequence not shown for spatial reasons. The 1-Mbp region from the telomeric end to the MDS locus (i.e., genes spanning from SCGB1C2 to TRARG1) in 17p13.3 is not shown. Schematic is not drawn to scale. Figure was created using BioRender [55].