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. 2025 Aug 13;20(8):e0328980. doi: 10.1371/journal.pone.0328980

Table 1. Baseline characteristics of survivors and deceased patients in the original cohort.

Variable Total (n = 13936) Alive (n = 12080) Death (n = 1856) p.value
MCV 93.25 ± 7.63 92.95 ± 7.45 95.23 ± 8.45 <0.0001
Sex 0.69
 Female 5364(38.49) 4658(38.56) 706(38.04)
 Male 8572(61.51) 7422(61.44) 1150(61.96)
Age (years) 73.40(63.38,82.20) 72.80(62.75,81.77) 76.72(67.72,84.25) <0.0001
Weight(kg) 80.00(67.80,96.00) 80.40(68.00,96.30) 77.75(66.00,93.85) <0.0001
Comorbidities
Heart failure <0.0001
 No 6209(44.55) 5519(45.69) 690(37.18)
 Yes 7727(55.45) 6561(54.31) 1166(62.82)
Respiratory failure <0.0001
 No 9345(67.06) 8661(71.70) 684(36.85)
 Yes 4591(32.94) 3419(28.30) 1172(63.15)
Arterial fibrillation <0.0001
 No 8052(57.78) 7145(59.15) 907(48.87)
 Yes 5884(42.22) 4935(40.85) 949(51.13)
Diabetes <0.01
 No 6486(46.54) 5561(46.03) 925(49.84)
 Yes 7450(53.46) 6519(53.97) 931(50.16)
Paraplegia 0.72
 No 13879(99.59) 12032(99.60) 1847(99.52)
 Yes 57(0.41) 48(0.40) 9(0.48)
Sepsis <0.0001
 No 10874(78.03) 9952(82.38) 922(49.68)
 Yes 3062(21.97) 2128(17.62) 934(50.32)
Stroke <0.0001
 No 13401(96.16) 11661(96.53) 1740(93.75)
 Yes 535(3.84) 419(3.47) 116(6.25)
TIA 1.00
 No 13895(99.71) 12044(99.70) 1851(99.73)
 Yes 41(0.29) 36(0.30) 5(0.27)
Laboratory tests
Hemoglobin, g/dL 9.87 ± 1.81 9.88 ± 1.79 9.83 ± 1.95 0.31
Platelet, K/uL 179.00(132.00,240.00) 180.00(134.00,239.00) 172.00(117.00,245.00) 0.03
RBC, m/uL 3.34 ± 0.65 3.35 ± 0.64 3.32 ± 0.70 0.15
WBC, K/uL 10.40(7.50,14.60) 10.10(7.40,14.00) 13.00(8.80,18.20) <0.0001
SCr, mg/dL 2.10(1.40,3.70) 2.00(1.40,3.60) 2.60(1.80,4.00) <0.01
FBG, mg/dL 131.00(105.00,175.00) 130.00(104.00,172.00) 144.00(111.00,203.00) <0.0001
Sodium, mEq/L 138.70 ± 5.00 138.66 ± 4.81 138.91 ± 6.11 0.09
SOFA 5.00(4.00,8.00) 5.00(3.00,7.00) 8.00(6.00,11.00) <0.0001
SAPSII 40.00(33.00,49.00) 39.00(32.00,47.00) 51.00(42.00,63.00) <0.0001
OASIS 32.29 ± 8.73 31.30 ± 8.20 38.72 ± 9.33 <0.0001
CCI 7.92 ± 2.39 7.79 ± 2.36 8.79 ± 2.37 <0.0001
Drug use
Epinephrine <0.0001
 No 13133(94.24) 11519(95.36) 1614(86.96)
 Yes 803(5.76) 561(4.64) 242(13.04)
Dopamine <0.0001
 No 13370(95.94) 11707(96.91) 1663(89.60)
 Yes 566(4.06) 373(3.09) 193(10.40)
Vasopressin <0.0001
 No 12773(91.65) 11479(95.02) 1294(69.72)
 Yes 1163(8.35) 601(4.98) 562(30.28)

Data are presented Standard Deviation (SE) or frequencies (percentages).

Abbreviation: MCV, mean corpuscular volume; SOFA, sequential organ failure assessment; CCI, Charlson comorbidity index; SAPSII, simplified acute physiological score II; OASIS, oxford acute severity of illness score; WBC, white blood cell; RBC, red blood cell; FBG, fasting blood glucose